Lancet
Volume 357, Issue 9266, 2001, Pages 1414-1415

Systemic lupus erythematosus in migrants from west Africa compared with Afro-Caribbean people in the UK (Article)

Molokhia M.* , McKeigue P.M. , Cuadrado M. , Hughes G.
  • a Epidemiology Unit, London Sch. Hyg. Trop. Med., W., London, United Kingdom
  • b Epidemiology Unit, London Sch. Hyg. Trop. Med., W., London, United Kingdom
  • c Rayne Institute, St Thomas' Hospital, London, United Kingdom
  • d Rayne Institute, St Thomas' Hospital, London, United Kingdom

Abstract

SLE has a high prevalence in Afro-Caribbean populations but has been reported to be rare in west Africa. We assessed prevalence (per 100 000) of SLE in women in an area of south London and estimated it to be 177 (95% Cl 135-220) in Afro-Caribbeans, 110 (58-163) in west Africans, and 35 (26-43) in Europeans. The high prevalence of SLE in recent migrants from west Africa suggests that the disease is not rare in west Africa, and that there is a genetic basis for the high risk of SLE in people of west African descent compared with other groups.

Author Keywords

[No Keywords available]

Index Keywords

clinical feature human sex difference controlled study priority journal Aged geographic distribution morbidity epidemiological data ethnic difference Adolescent male female Africa questionnaire Article adult migration systemic lupus erythematosus United Kingdom age distribution Caribbean Islands
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035810616&doi=10.1016%2fS0140-6736%2800%2904580-3&partnerID=40&md5=2ffd35f9737b2983e858a0bce5f4bc57
DOI: 10.1016/S0140-6736(00)04580-3
ISSN: 01406736
Cited by: 58
Original Language: English