Medicinski arhiv
Volume 55, Issue 1 Suppl 1, 2001, Pages 35-38

Sertralilne, paroxetine and venlafaxine in refugee post traumatic stress disorder with depression symptoms. (Article)

Smajkić A.* , Weine S. , Durić-Bijedić Z. , Boskailo E. , Lewis J. , Pavković I.
  • a Project on Genocide, Psychiatry and Witnessing, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, United States
  • b Project on Genocide, Psychiatry and Witnessing, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, United States
  • c Project on Genocide, Psychiatry and Witnessing, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, United States
  • d Project on Genocide, Psychiatry and Witnessing, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, United States
  • e Project on Genocide, Psychiatry and Witnessing, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, United States
  • f Project on Genocide, Psychiatry and Witnessing, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, United States

Abstract

The authors describe the use of three new antidepressants: Sertralilne, Paroxetine and Venlafaxine in treating Posttraumatic Stress Disorder and symptoms of Depression in adult Bosnian refugees victims of ethnic cleansing. 32 Bosnian refugees with PTSD and symptoms of Depression presenting for treatment of the mental health consequences of surviving ethnic cleansing, participated in a case series study. All subjects completed open trials of Sertraline (15), Paroxetine (12) or Venlafaxine (5), with standard clinical doses. Overall, Sertraline and Paroxetine yielded statistically significant improvement at 6 weeks in the total PTSD symptom severity, in each symptom cluster, in Beck Depression Inventory and in Global Assessment of Functioning. Venlafaxine produced statistically significant improvement at 6 weeks in the total PTSD symptom severity, in each symptom cluster and in Global Assessment of Functioning but did not yield significant improvement in symptoms of depression and had a high rate of side effects.

Author Keywords

[No Keywords available]

Index Keywords

depression refugee psychological aspect human Refugees middle aged war Serotonin Uptake Inhibitors comparative study Bosnia and Herzegovina Depressive Disorder ethnology Bosnia-Herzegovina United States cyclohexanol derivative venlafaxine Humans male female pilot study sertraline Antidepressive Agents paroxetine Article Cyclohexanols adult posttraumatic stress disorder Stress Disorders, Post-Traumatic serotonin uptake inhibitor antidepressant agent Pilot Projects
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035752387&partnerID=40&md5=123e4316526e47b87b359cac36c99cb8
ISSN: 0350199X
Cited by: 6
Original Language: English