Respiratory Physiology and Neurobiology
Volume 206, 2015, Pages 4-10

Sleep disturbances in long-term immigrants with chronic mountain sickness: A comparison with healthy immigrants at high altitude (Article)

Guan W. , Ga Q. , Li R. , Bai Z.-Z. , Wuren T. , Wang J. , Yang Y.-Z. , Li Y.-H. , Ge R.-L.*
  • a Research Center for High Altitude Medicine, Qinghai University, Xining, 810001, China, Department of Respiratory Medicine, The Affiliated Hospital of Qinghai University, Xining, 810001, China
  • b Research Center for High Altitude Medicine, Qinghai University, Xining, 810001, China
  • c Department of Respiratory Medicine, The Affiliated Hospital of Qinghai University, Xining, 810001, China
  • d Research Center for High Altitude Medicine, Qinghai University, Xining, 810001, China
  • e Research Center for High Altitude Medicine, Qinghai University, Xining, 810001, China
  • f The Military Department of China Armed Police Forces Hospital of Qinghai Province, Xining, 810000, China
  • g Research Center for High Altitude Medicine, Qinghai University, Xining, 810001, China
  • h Research Center for High Altitude Medicine, Qinghai University, Xining, 810001, China, Department of Respiratory Medicine, The Affiliated Hospital of Qinghai University, Xining, 810001, China
  • i Research Center for High Altitude Medicine, Qinghai University, Xining, 810001, China

Abstract

The aim of this study was to examine sleep disturbances in patients with chronic mountain sickness (CMS). The sleep of 14 patients with CMS and 11 healthy controls with or without sleep disorders (control N: without sleep disorders; control D: with sleep disorders) was studied by polysomnography. Hypopnea was the sleep disorder most commonly suffered by CMS patients and control D subjects. No major differences were observed in sleep structure between CMS and control groups, with the exception of shorter rapid eye movement latency in controls and increased deep non-rapid eye movement in the control N group. Periodic breathing was observed in only two study participants, one each in the CMS and control D groups. The level of saturated oxygen was significantly lower in the CMS group during sleep than the control groups (P<. 0.05). CMS scores were positively correlated with the apnea-hypopnea index, and negatively correlated with saturated oxygen levels. These results demonstrate that sleep disorders and nocturnal hypoxia are important in the development of CMS. © 2014 Elsevier B.V.

Author Keywords

immigrants Sleep disorder Rapid eye movement High elevation Chronic mountain sickness

Index Keywords

Altitude immigrant oxygen consumption complication Altitude Sickness polysomnography human lung function apnea hypopnea index middle aged statistics altitude disease REM sleep breathing controlled study oxygen desaturation Statistics as Topic chronic disease Respiration Humans migrant sleep disorder male Emigrants and Immigrants female clinical article Article adult body mass Sleep Disorders
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84912051390&doi=10.1016%2fj.resp.2014.11.007&partnerID=40&md5=4a7a56177fe50250a65cb36a16621527
DOI: 10.1016/j.resp.2014.11.007
ISSN: 15699048
Cited by: 10
Original Language: English