Annali dell'Istituto Superiore di Sanita
Volume 51, Issue 4, 2015, Pages 327-335

A cost-consequence analysis of hepatitis B screening in an immigrant population (Article)

Buja A.* , Martines D. , Lobello S. , Vinelli A. , Bardelle G. , Lopatriello S. , De Lazzari F. , Perrier L. , Baldo V.
  • a Dipartimento di Medicina Molecolare, Università degli Studi di Padova, Via Loredan 18, Padua, 35128, Italy
  • b Dipartimento di Gastroenterologia, ASL 16 Ospedale Generale, Regione Veneto, Padua, Italy
  • c Dipartimento di Gastroenterologia, ASL 16 Ospedale Generale, Regione Veneto, Padua, Italy
  • d Dipartimento di Medicina Molecolare, Università degli Studi di Padova, Via Loredan 18, Padua, 35128, Italy
  • e Dipartimento di Medicina Molecolare, Università degli Studi di Padova, Via Loredan 18, Padua, 35128, Italy
  • f Pharmacist, freelance economic consultant, France
  • g Dipartimento di Medicina Molecolare, Università degli Studi di Padova, Via Loredan 18, Padua, 35128, Italy
  • h Clinical Research and Innovation Direction, Léon Bérard Cancer Centre, Lyon, France
  • i Dipartimento di Medicina Molecolare, Università degli Studi di Padova, Via Loredan 18, Padua, 35128, Italy

Abstract

Objective. Screening for HBV among groups at risk, such as migrant populations, has proved to be a cost-effective strategy With a view to advising local policy-makers, the cost-consequences of HBV screening was assessed using a modeling approach. Methods. This cost-consequence analysis of an HBV screening strate' was conducted in a cohort of adult migrants in the province of Padua, northern Italy. Results. The population targeted for screening consisted of 65405 migrants, among whom the weighted rate for the prevalence of HBV was 0.04972, with 3251 people infected. Over a period of 5 years, the screening strater prevented 565 cases/year of chronic hepatitis, 141 of compensated cirrhosis. 9 of decompensated cirrhosis. 14 hepatocellular carcinomas and 12 deaths. The above data revealed that the incremental cost of the screening strate, compared to no screening strategy was € 7 974 959 over the five year period. The cost per life saved amounted to € 676 709. Conclusions. The present study provides useful information to policy-makers at local and regional levels.

Author Keywords

immigrants health care services Modeling Cost-conseqticncc analysis Screening program

Index Keywords

Emigrants and Immigrants Liver Neoplasms cohort analysis Italy Humans Cost benefit analysis vaccination mass screening economics prevalence hepatitis B cost-benefit analysis Carcinoma, Hepatocellular liver cirrhosis human adult migrant Cohort Studies
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954430000&doi=10.4415%2fANN-15-04-13&partnerID=40&md5=04f0fb1af0b31a4ba9526794ce75d2d2
DOI: 10.4415/ANN-15-04-13
ISSN: 00212571
Cited by: 1
Original Language: English