Arquivos Brasileiros de Cardiologia
Volume 81, Issue 3, 2003, Pages 229-238

Coronary heart disease clinical manifestation and risk factors in Japanese immigrants and their descendents in the city of São Paulo [Manifestação clínica da doença coronariana e fatores de risco em imigrantes Japoneses e seus descendentes em São Paulo] (Article)

Amato R.V.* , Machado César L.A. , De Pádua Mansur A. , Armindo Hueb W. , Martines Martins J.R. , De Brito Vianna C. , Franchini Ramires J.A.
  • a INCOR, Unidade Clin. Coronariopatia Cronica, Divisão Clínica, Av Dr Eneas C Aguiar, 44, 05403-000 - São Paulo, Brazil
  • b [Affiliation not available]
  • c [Affiliation not available]
  • d [Affiliation not available]
  • e [Affiliation not available]
  • f [Affiliation not available]
  • g [Affiliation not available]

Abstract

Objective - To assess whether a difference exists in coronary heart disease clinical manifestations and the prevalence of risk factors between Japanese immigrants and their descendents in the city of São Paulo. Methods - Retrospective analysis of coronary artery disease clinical manifestations and the prevalence of risk factors, comparing 128 Japanese immigrants (Japanese group) with 304 Japanese descendents (Nisei group). Results - The initial manifestation of the disease was earlier in the Nisei group (mean = 53 years), a difference of 12 years when compared with that in the Japanese group (mean = 65 years) (P<0.001). Myocardial infarction was the first manifestation in both groups (P = 0.83). The following parameters were independently associated with early coronary events: smoking (OR = 2.25; 95% CI = 1.35-3.77; P<0.002); Nisei group (OR = 10.22; 95% CI = 5.64-18.5; P<0.001); and female sex (OR = 5.04; 95% CI = 2.66-9.52; P<0.001). Conclusion - The clinical presentation of coronary heart disease in the Japanese and their descendents in the city of São Paulo was similar, but coronary heart disease onset occurred approximately 12 years earlier in the Nisei group than in the Japanese group.

Author Keywords

coronary heart disease Diabetes mellitus Systemic arterial hypertension Hypertriglyceridemia Hypercholesterolemia

Index Keywords

immigrant hypercholesterolemia cardiovascular risk heart infarction clinical feature human middle aged controlled study Aged Humans smoking male Japan Hypertriglyceridemia female Aged, 80 and over risk factor Age of Onset Risk Factors prevalence Article Retrospective Studies major clinical study adult ischemic heart disease Brazil Coronary Disease
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0141995765&partnerID=40&md5=75ce700a1120777d95ad8af48de35b77
ISSN: 0066782X
Cited by: 4
Original Language: Portuguese; English