Tropical Medicine and International Health
Volume 8, Issue 4, 2003, Pages 316-321

Long-term population migration: An important aspect to be considered during mass drug administration for elimination of lymphatic filariasis (Article)

Sunish I.P. , Rajendran R. , Mani T.R. , Gajanana A. , Reuben R. , Satyanarayana K.*
  • a Ctr. for Res. in Medical Entomology, Madurai, India, Ctr. for Res. in Medical Entomology, Indian Council of Medical Research, Chinna Chokkikulam, 9/4 Sarojini Street, Madurai 625 002, Tamil Nadu, India
  • b Ctr. for Res. in Medical Entomology, Madurai, India, Ctr. for Res. in Medical Entomology, Indian Council of Medical Research, Chinna Chokkikulam, 9/4 Sarojini Street, Madurai 625 002, Tamil Nadu, India
  • c Ctr. for Res. in Medical Entomology, Madurai, India, Ctr. for Res. in Medical Entomology, Indian Council of Medical Research, Chinna Chokkikulam, 9/4 Sarojini Street, Madurai 625 002, Tamil Nadu, India
  • d Retired Officer Ctr. Res. Med. E., Madurai, India, 11th Main Road, Hanumantha Nagar, Bangalore 560 019, India
  • e Retired Officer Ctr. Res. Med. E., Madurai, India, 52, Rashmi Apartments, D'Monte Park Road, Bandra, Mumbai 400 050, India
  • f Ctr. for Res. in Medical Entomology, Madurai, India, Ctr. for Res. in Medical Entomology, Indian Council of Medical Research, Chinna Chokkikulam, 9/4 Sarojini Street, Madurai 625 002, Tamil Nadu, India

Abstract

Annual 2-drug, single-dose mass drug administration (MDA) to 80-90% of the eligible population for 4-6 years are pre-requisites for the successful elimination of lymphatic filariasis (LF) from endemic communities by interruption of transmission and eventual elimination of new infections. In an experimental intervention project on the control of LF in Villupuram district of Tamil Nadu state, India, migration patterns of the villagers were investigated to determine the appropriate timing to implement MDA in order to attain high coverage in a village-level study. Between January and December 1997, 16 observations took place at 3-week intervals, following MDA with two drugs viz., diethylcarbamazine and ivermectin, in July-August 1996. The migrants from the village constituted 17-27% at different points of time and both short-term and long-term migrating patterns were observed. More villagers were available during the agricultural season (September-January), peaking around mid-January [83%; significantly higher (P < 0.05)] than during most of the remaining months, including a substantial portion of the migrant population. There is an urgent need to reschedule the yearly MDA in this area to take place in January and to plan mopping up operations by involving local self-help groups to include migrants (both short-term and long-term) in the LF elimination efforts.

Author Keywords

Human migration Lymphatic filariasis Mass drug administration

Index Keywords

filariasis drug prescribing bacterial transmission India human middle aged diethylcarbamazine Bacteria (microorganisms) ivermectin population structure Elephantiasis, Filarial Seasons rural health Drug Administration Schedule Humans Adolescent male female Filaricides Protozoa Article Drug Therapy, Combination disease control infection control major clinical study adult Sex Distribution age distribution Transients and Migrants population migration Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037398841&doi=10.1046%2fj.1365-3156.2003.01033.x&partnerID=40&md5=85ce3414b1beed35ba3d2d700d076b75
DOI: 10.1046/j.1365-3156.2003.01033.x
ISSN: 13602276
Cited by: 17
Original Language: English