Farmacia
Volume 66, Issue 3, 2018, Pages 537-540

The impact of migrant tuberculosis on the chimioresistance pattern of antituberculosis drugs in a low burden tuberculosis european country (Article)

Arghir O.-C. , Pereira P.M.A. , Rașcu A.* , Dantes E. , Borgazi E. , Iliescu D.M. , Oțelea M.R. , Cambrea S.C.
  • a Medicine Faculty, “Ovidius” University of Constanța, 124, Mamaia Blvd, Constanța, 900527, Romania, Clinical Hospital of Pneumophthisiology, 40, Sentinelei Street, Constanța, 900002, Romania
  • b Fellow-in Training Hospital de Faro, Algarve, Portugal
  • c “Carol Davila” University of Medicine and Pharmacy Bucharest, Dionisie Lupu Street, sector 1, Bucharest, 030167, Romania
  • d Medicine Faculty, “Ovidius” University of Constanța, 124, Mamaia Blvd, Constanța, 900527, Romania, Clinical Hospital of Pneumophthisiology, 40, Sentinelei Street, Constanța, 900002, Romania
  • e Clinical Hospital of Pneumophthisiology, 40, Sentinelei Street, Constanța, 900002, Romania
  • f Medicine Faculty, “Ovidius” University of Constanța, 124, Mamaia Blvd, Constanța, 900527, Romania
  • g “Carol Davila” University of Medicine and Pharmacy Bucharest, Dionisie Lupu Street, sector 1, Bucharest, 030167, Romania
  • h Medicine Faculty, “Ovidius” University of Constanța, 124, Mamaia Blvd, Constanța, 900527, Romania

Abstract

The issue of drug resistance (DR) among patients with tuberculosis (TB) has occurred since the introduction of streptomycin and becomes a priority for TB control programs worldwide. Based on Portugal National Tuberculosis Surveillance System (SVIG-TB) and regional drug sensitivity testing (DST) database, a 10 year-epidemiological survey described retrospectively the impact of DR phenomenon on TB trend in Algarve, Portugal, from 01 January 2004 to 31 December 2014. Study sample included 106 patients with male (78%) and youth predominance. The most important risk factor for DR-TB consisted in immigration (31.13%). © 2018, Romanian Society for Pharmaceutical Sciences. All rights reserved.

Author Keywords

Drug-resistance First line tuberculostatic drugs Migrant tuberculosis

Index Keywords

human clinical assessment Young Adult lung tuberculosis tuberculostatic agent male female tuberculosis Article streptomycin drug sensitivity major clinical study adult isoniazid thorax radiography outcome assessment retrospective study rifampicin clinical effectiveness
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049468554&partnerID=40&md5=0852e373d47b957f10bf37c5a627f1fc
ISSN: 00148237
Cited by: 1
Original Language: English