Zeitschrift fur Gastroenterologie
Volume 56, Issue 12, 2018, Pages 1499-1506

Colorectal cancer stage at diagnosis in migrants and non-migrants: A cross-sectional analysis of the KoMigra Study in Germany (Article)

Dahlhaus A. , Siebenhofer A.* , Guethlin C. , Taubenroth M. , Albay Z. , Schulz-Rothe S. , Singer S. , Plath J.
  • a Institute of General Practice, Goethe University Frankfurt Am Main, Frankfurt, Germany
  • b Institute of General Practice, Goethe University Frankfurt Am Main, Frankfurt, Germany, Institute of General Practice and Evidence-Based Health Services Research, Medical University Graz, Auenbruggerplatz 2/9, Graz, A-8036, Austria
  • c Institute of General Practice, Goethe University Frankfurt Am Main, Frankfurt, Germany
  • d Institute of General Practice, Goethe University Frankfurt Am Main, Frankfurt, Germany
  • e Institute of General Practice, Goethe University Frankfurt Am Main, Frankfurt, Germany
  • f Institute of General Practice, Goethe University Frankfurt Am Main, Frankfurt, Germany
  • g Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), Mainz, Germany, German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Germany
  • h Institute of General Practice, Goethe University Frankfurt Am Main, Frankfurt, Germany, German Cancer Research Center (DKFZ), Heidelberg, Germany, German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Germany

Abstract

Background Colorectal cancer is one leading cause of cancer-related morbidity and mortality. Its prognosis depends largely on tumour stage at diagnosis. Migration status was associated with late stage at diagnosis in some studies, yet results are inconsistent. Methods The cross-sectional study The Diagnostics of Colorectal Carcinoma in Migrants and Non-Migrants in Germany (KoMigra) investigated the association between migration background and tumour stage of colorectal cancer at diagnosis in a large German urban area. Patient variables were collected via a survey translated into nine languages. Data on tumour stage were extracted from medical records. Results 437 patients could be recruited for analysis. Explorative logistic regression yielded no significant difference for tumour stage I versus II-IV according to the tumour classification Union Internationale Contre le Cancer (UICC) between migrants and non-migrants. Although the odds of a higher tumour stage were consistently higher in migrants than non-migrants, the effect estimates had wide confidence intervals. In descriptive analyses, migrants reported symptoms more often and for longer time than non-migrants. This was especially true for patients with poor proficiency of German. Conclusions Migration background was not significantly associated with advanced tumour stage at diagnosis. However, the effect of poor language proficiency should be explored further. © Georg Thieme Verlag KG.

Author Keywords

Colorectal cancer Migrants cross-sectional analysis UICC tumor stage

Index Keywords

Germany patient information multicenter study cancer prognosis human Neoplasm Staging delayed diagnosis colorectal cancer colorectal tumor controlled study cancer staging Aged Colorectal Neoplasms cancer screening morbidity Cross-Sectional Studies cross-sectional study migrant Humans male female questionnaire Article cancer mortality major clinical study adult migration tumor classification cancer diagnosis Transients and Migrants
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85058613297&doi=10.1055%2fa-0655-2352&partnerID=40&md5=fd3bd823a1ed5c3c083a9dd49bc58b85
DOI: 10.1055/a-0655-2352
ISSN: 00442771
Original Language: English