Acta Tropica
Volume 195, 2019, Pages 23-27

Leishmaniasis in Istanbul; A new epidemiological data about refugee leishmaniasis (Article)

Çizmeci Z. , Karakuş M.* , Karabela Ş.N. , Erdoğan B. , Güleç N.
  • a Department of Medical Microbiology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey
  • b Department of Biotechnology, Health Sciences Institute, University of Health Sciences, Istanbul, Turkey
  • c Department of Infectious Diseases and Clinical Microbiology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey
  • d Department of Dermatology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey
  • e Department of Medical Microbiology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey

Abstract

Leishmania is an intracellular parasite, which is transmitted by the bite of infected female Phlebotominae sand flies. Turkey is a crossroad between Europe and Asia that makes it important in terms of epidemiology. In the present study, we aimed to evaluate Leishmania infection among non-autochthonous patients admitted to Health Sciences University, Dr. Sadi Konuk Research and Training hospital between 2014−2018. Slides were prepared by sampling the edge of the lesions for each patient. Microscopical examination was performed after staining procedures. After microscopical examination slides were washed and DNA extraction was performed. ITS-1 real-time PCR was performed to identify the species of the causative agents. Demographic data were recorded for each patient. Also number, type and location of the lesions were recorded. Totally 13 patients were included in this. Majority (12/13) of them were found to be infected with L. tropica, while one patient was infected with L. infantum. Two of the lesions were wet type and 11 of them were dry type lesions. Several papers were published recently about leishmaniasis in Turkey but to best of our knowledge, this is the first study reporting refugee leishmaniasis in İstanbul. © 2019 Elsevier B.V.

Author Keywords

Turkey Leishmania tropica Refugee İstanbul

Index Keywords

genetics hospital admission refugee DNA extraction sampling demography university hospital human epidemiology Refugees controlled study Turkey (republic) Animals nonhuman Giemsa stain animal epidemiological data Young Adult school child Humans Adolescent male female stibogluconate sodium clinical article polymerase chain reaction leishmaniasis Article DNA adult microscopy Turkey turkey (bird) internal transcribed spacer 1 meglumine antimonate Leishmania Leishmania infantum Phlebotominae Istanbul [Turkey] Leishmania tropica real time polymerase chain reaction Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064493394&doi=10.1016%2fj.actatropica.2019.04.008&partnerID=40&md5=46ddf0118b046cd3d01f1fb227062528
DOI: 10.1016/j.actatropica.2019.04.008
ISSN: 0001706X
Cited by: 1
Original Language: English