Travel Medicine and Infectious Disease
Volume 29, 2019, Pages 40-47
Travel-related health events and their risk factors in HIV-infected sub-Saharan migrants living in France and visiting their native country: The ANRS VIHVO cohort study (Article) (Open Access)
Pistone T.* ,
Ouattara E. ,
Gabillard D. ,
Lele N. ,
Duvignaud A. ,
Cordel H. ,
Malvy D. ,
Bouchaud O. ,
Abgrall S. ,
Bentata M. ,
Fantin B. ,
Goujard C. ,
Matheron S. ,
Launay O. ,
Le Moing V. ,
Lortholary O. ,
Consigny P.-H. ,
Saada M. ,
Katlama C. ,
Simon A. ,
Arvieux C. ,
Campa P. ,
Girard P.-M. ,
Khuong M.-A. ,
Molina J.-M. ,
Lascoux-Combe C. ,
Rey D. ,
Rondeau M. ,
Pialoux G. ,
Couzigou C. ,
Vittecoq D. ,
Patey O. ,
Morlat P. ,
Duong M. ,
Chavanet P. ,
ANRS VIHVO Study Group
-
a
CHU Bordeaux, Department for Infectious and Tropical Diseases, Bordeaux, 33000, France, Inserm U1219, Infectious Diseases in Lower Income Countries (IDLIC), Université de Bordeaux, 146 rue Léo-Saignat, Bordeaux cedex, 33076, France
-
b
CHU Bordeaux, Department for Infectious and Tropical Diseases, Bordeaux, 33000, France, Inserm U1219, Infectious Diseases in Lower Income Countries (IDLIC), Université de Bordeaux, 146 rue Léo-Saignat, Bordeaux cedex, 33076, France
-
c
Inserm U1219, Infectious Diseases in Lower Income Countries (IDLIC), Université de Bordeaux, 146 rue Léo-Saignat, Bordeaux cedex, 33076, France
-
d
AP-HP, Service des Maladies Infectieuses et Tropicales, Hôpital Avicenne, Bobigny, 93000, France, Université Paris 13, Bobigny, France
-
e
CHU Bordeaux, Department for Infectious and Tropical Diseases, Bordeaux, 33000, France, Inserm U1219, Infectious Diseases in Lower Income Countries (IDLIC), Université de Bordeaux, 146 rue Léo-Saignat, Bordeaux cedex, 33076, France
-
f
AP-HP, Service des Maladies Infectieuses et Tropicales, Hôpital Avicenne, Bobigny, 93000, France, Université Paris 13, Bobigny, France
-
g
CHU Bordeaux, Department for Infectious and Tropical Diseases, Bordeaux, 33000, France, Inserm U1219, Infectious Diseases in Lower Income Countries (IDLIC), Université de Bordeaux, 146 rue Léo-Saignat, Bordeaux cedex, 33076, France
-
h
AP-HP, Service des Maladies Infectieuses et Tropicales, Hôpital Avicenne, Bobigny, 93000, France, Université Paris 13, Bobigny, France
-
i
AP-HP, Hôpital Antoine Béclère, Clamart, France, Inserm U1018, Centre de recherche en Epidémiologie et Santé des Populations (CESP), Le Kremlin-Bicêtre Cedex, Université Paris Sud University, Paris Saclay University, France
-
j
CHU Avicenne, Bobigny, France
-
k
CHU Beaujon, Clichy, France
-
l
CHU Bicêtre, Le Kremlin-Bicêtre, France
-
m
CHU Bichat, Paris, France
-
n
CHU Cochin, Paris, France
-
o
CHU de Montpellier, Montpellier, France
-
p
CHU Necker, Paris, France
-
q
CHU Pasteur, Paris, France
-
r
Hôpital de Perpignan, Perpignan, France
-
s
CHU Pitié-Salpétrière, Paris, France
-
t
CHU Pitié-Salpétrière, Paris, France
-
u
CHU de Rennes, Rennes, France
-
v
CHU Saint-Antoine, Paris, France
-
w
CHU Saint-Antoine, Paris, France
-
x
Hôpital De Lafontaine, Saint- Denis, France
-
y
CHU Saint-Louis, Paris, France
-
z
CHU Saint-Louis, Paris, France
-
a
Hôpital Civil, Strasbourg, France
-
b
Hôpital Civil, Strasbourg, France
-
c
CHU Tenon, Paris, France
-
d
CHU Paul Brousse, Villejuif, France
-
e
CHU Paul Brousse, Villejuif, France
-
f
Hôpital de Villeneuve Saint Georges, Villeneuve saint Georges, France
-
g
CHU Bordeaux, Bordeaux, France
-
h
CHU Dijon, Dijon, France
-
i
CHU Dijon, Dijon, France
-
j
[Affiliation not available]
Abstract
Background: Literature on health events in HIV-infected travellers is scarce, particularly in sub-Saharan African (SSA) migrants. Methods: We investigated health events in HIV-infected SSA migrants living in France during and after travel to their native country. All had a pre-travel plasma viral load (pVL) below 200 copies/mL and were on stable combined antiretroviral therapy (cART). Logistic regression models were used to assess the risk factors for at least one adverse health event or febrile event. Results: Among 264 HIV migrants, pre-travel median CD4 count was 439/mm3 and 27 migrants (6%) experienced a low-level viremia between 50 and 200 copies/mL. One hundred (38%) experienced at least one event (13 experienced two events). The most common events were gastrointestinal, including diarrhoea (n = 29, 26%), respiratory events (n = 20, 18%), and malaria (n = 17, 15%; 1 death). In multivariable analysis, a pre-travel low-level viremia and a lack of pre-travel medical advice significantly increased the risk for any event (OR 4.31, 95% CI, 1.41–13.1; and OR 3.62, 95% CI, 1.38–9.47; respectively). A lack of pre-travel advice significantly increased the risk for febrile event. Conclusions: Early and tailored counselling on pre-travel medical advice regarding diarrhoea and vector-borne diseases prophylactic measures in HIV-infected SSA migrants should be emphasised before travel to Africa. © 2019 The Authors
Author Keywords
Index Keywords
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064468371&doi=10.1016%2fj.tmaid.2019.03.010&partnerID=40&md5=cb169040f5d4ed11eaf4d5bddd2851f7
DOI: 10.1016/j.tmaid.2019.03.010
ISSN: 14778939
Cited by: 1
Original Language: English