Background: Traumatized refugees with comorbid pain report more severe posttraumatic stress disorder (PTSD), respond less well to PTSD-focused treatments and exhibit greater disability. A mutually maintaining relationship may exist between pain and PTSD, that may be partly accounted for by depression, but no prior studies have tested this assumption in traumatized refugees. Method: Self-report measures of pain, PTSD, depression, disability, pain catastrophizing (PC) and trauma-related beliefs (TRBs) were administered to 197 refugees referred to the Danish Institute Against Torture (DIGNITY) prior to treatment. The contribution of pain, depression, PC, and TRBs to the overall variance in PTSD severity was examined. We also examined whether the relationship between pain and PTSD was mediated by PC and TRBs, after controlling for depression. Results: Depression, pain severity, PC and TRBs together accounted for 66% of the overall variance in PTSD, with depression being the primary contributor (57%). In univariate tests, both PC and TRBs significantly mediated the relationship between pain interference/severity and PTSD. However, after controlling for depression only PC mediated this relationship. Conclusions: Negative beliefs about pain and the trauma made small, but additive contributions to the relationship between pain and PTSD severity, after controlling for depression. Longitudinal studies with refugees, involving tests of more complex mutual maintenance models, are warranted. Significance: After controlling for symptoms of depression, pain catastrophizing and negative trauma-related beliefs partly mediated the relationship between pain and PTSD in tortured refugees. The results suggest that all three variables are important in a mutual mediation model of pain and PTSD, and as targets for treatment, in traumatized refugees. © 2019 European Pain Federation - EFIC®

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depression refugee anxiety disorder human Self Report injury health belief controlled study pain priority journal torture survivor functional status assessment cross-sectional study preliminary data pain catastrophizing Coping Strategies Questionnaire 24 World Health Organization Disability Assessment Schedule 2.0 catastrophizing male posttraumatic cognitions inventory Brief Pain Inventory female coping behavior assesment Harvard Trauma Questionnaire Article Symptom Assessment major clinical study adult pain severity posttraumatic stress disorder anxiety assessment disability Hopkins Symptom Checklist 25 disease severity disease association psychotrauma assessment