Turkiye Klinikleri Journal of Medical Sciences
Volume 39, Issue 2, 2019, Pages 160-164

Cutaneous leishmaniasis: Evaluation of 117 syrian immigrants [Kutanöz Layşmanyazis: 117 Suriye’li Hastamn Değerlendirilmesi] (Article) (Open Access)

Karaosmanoğlu N.* , Şahın M. , Vahaboğlu G. , Akbay G. , Edgüer E.Y. , Şahın T. , Tanaçan F.E. , Ekşıoğlu H.M. , Adıloğlu A.K.
  • a Clinics of Dermatology, Ankara Training and Research Hospital, Ankara, Turkey
  • b Clinics of Dermatology, Ankara Training and Research Hospital, Ankara, Turkey
  • c Clinics of Dermatology, Ankara Training and Research Hospital, Ankara, Turkey
  • d Clinics of Dermatology, Ankara Training and Research Hospital, Ankara, Turkey
  • e Clinics of Dermatology, Ankara Training and Research Hospital, Ankara, Turkey
  • f Clinics of Dermatology, Ankara Training and Research Hospital, Ankara, Turkey
  • g Clinics of Dermatology, Ankara Training and Research Hospital, Ankara, Turkey
  • h Clinics of Dermatology, Ankara Training and Research Hospital, Ankara, Turkey
  • i Clinics of Microbiology, Ankara Training and Research Hospital, Ankara, Turkey

Abstract

Objective: Cutaneous leishmaniasis (CL), which presents with nodulo-ulcerative lesions in the skin, is an endemic disease in Syria and in some of the regions of Turkey. The aim of this study was to evaluate the demographic and clinical characteristics, type of treatment and treatment responses of 117 CL patients. Material and Methods: In this study, 117 Syrian CL patients, who applied to the outpatient clinic were presented. Results: Sixty two of the patients were female (53%) and 55 (% 47) were male. The mean age of the patients was 16±1,4. Fifty two point one percent of the patients had one, 38.5% had two or three and 9.4% had more than three lesions. The mean duration of the lesions was 7 months, while the average duration of residence time in Turkey was 6 months. Ninety six point six percent of the lesions had a diameter less than 5 cm and the rest had larger lesions. Most of the lesions were localized on the face (43.1%) and extremities (42.8%). The majority of the lesions on the face were at the cheeks (53.8%), one of them was on the eyelid, 2 on the lip, 4 on the ear and 9 on the nose. The patients were treated with intralesional antimony compounds or cryotherapy. Lesions of the patients, who were treated with the antimony compounds recovered faster and with superior cosmetic results. Conclusion: Intralesional antimone therapy is an effective and cosmetically successful treatment option without any significant side effects for CL. © 2019 by Türkiye Klinikleri.

Author Keywords

Leishmaniasis Cryotherapy Intralesional Cutaneous Injections

Index Keywords

treatment response immigrant retention time papule human limb drug efficacy disease duration skin defect Adolescent male female Article major clinical study adult skin leishmaniasis cryotherapy cytokine systemic therapy antimony derivative face Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071011918&doi=10.5336%2fmedsci.2018-63210&partnerID=40&md5=a67a7bd7bdf8f4ed4abc51eed99d0d28
DOI: 10.5336/medsci.2018-63210
ISSN: 13000292
Original Language: English