Ocular Surface
Volume 17, Issue 1, 2019, Pages 83-88

Ethnic differences between the Asian and Caucasian ocular surface: A co-located adult migrant population cohort study (Article)

Craig J.P.* , Lim J. , Han A. , Tien L. , Xue A.L. , Wang M.T.M.
  • a Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand
  • b Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand
  • c Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand, School of Optometry and Vision Science, New Zealand National Eye Centre, The University of Auckland, New Zealand
  • d Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand, School of Optometry and Vision Science, New Zealand National Eye Centre, The University of Auckland, New Zealand
  • e Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand
  • f Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand

Abstract

Purpose: To investigate the ethnic differences in tear film quality, ocular surface parameters, and dry eye symptomology between co-located Asian and Caucasian populations. Methods: Two hundred and six participants (103 East Asian and 103 Caucasian) were recruited in an age and gender-matched cross-sectional study. Dry eye symptomology, ocular surface parameters, and tear film quality were evaluated for each participant within a single clinical session. Results: The mean ± SD age of the 206 participants (82 male, 124 female) was 45 ± 16 years. Overall, a greater proportion of Asian participants were symptomatic of dry eye and fulfilled the TFOS DEWS II dry eye diagnostic criteria than Caucasian participants (74% versus 51%, p = 0.002), with an odds ratio (95% CI) of 2.7 (1.5–4.8) times. Poorer OSDI scores, tear film stability, lipid layer quality, tear osmolarity, lid wiper epitheliopathy, meibomian gland dropout, and expressed meibum quality were observed in the Asian group (all p < 0.05). A significantly higher proportion of participants exhibited incomplete blinking in the Asian group than the Caucasian group (81% versus 45%, p < 0.001). Conclusions: Asian participants exhibited more severe dry eye signs and symptoms than Caucasian participants. The poorer meibomian gland function and higher degree of incomplete blinking observed among Asian participants may potentially contribute towards the ethnic predisposition towards dry eye development. © 2018 Elsevier Inc.

Author Keywords

Ethnicity Eyelid Meibomian gland Ocular surface Dry eye Tear film

Index Keywords

lifestyle Asian dry eye Caucasian mcmonnies dry eye questionnaire knee meniscus dry eye questionnaire tear osmolarity Ocular Surface Disease Index visual system parameters ocular surface disease knee meniscus rupture human cross-sectional study ethnic difference male female questionnaire Article major clinical study adult age cohort analysis
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053889290&doi=10.1016%2fj.jtos.2018.09.005&partnerID=40&md5=a95304efd2adaea8deb88c7ed2f42c7b
DOI: 10.1016/j.jtos.2018.09.005
ISSN: 15420124
Cited by: 3
Original Language: English