Internist
Volume 57, Issue 8, 2016, Pages 811-814

Peranal bleeding and elevated liver function tests in a 33‑year-old refugee from Nigeria [Peranaler Blutabgang und erhöhte Leberwerte bei einem 33‑jährigen Flüchtling aus Nigeria] (Article)

Argirovic N.* , Caselitz M. , Mohren W. , Cruz Cordero F. , Huber J. , Wagner S.
  • a Medizinische Klinik II, Donauisar Klinikum, Perlasberger Str. 41, Deggendorf, 94469, Germany
  • b Medizinische Klinik II, Donauisar Klinikum, Perlasberger Str. 41, Deggendorf, 94469, Germany
  • c Institut für Pathologie und Zytologie, Donauisar Klinikum, Deggendorf, Germany
  • d Institut für Pathologie und Zytologie, Donauisar Klinikum, Deggendorf, Germany
  • e Institut für Laboratoriumsdiagnostik und Transfusionsmedizin, Donauisar Klinikum, Deggendorf, Germany
  • f Medizinische Klinik II, Donauisar Klinikum, Perlasberger Str. 41, Deggendorf, 94469, Germany

Abstract

A 33-year-old refugee from Nigeria, who had been living in Germany for 1 year, was admitted to the hospital due to pelvic pain, peranal hemorrhage, and an unexplained increase in transaminase levels. As the liver screening tests, sonography findings, and colonoscopy were normal, a liver biopsy was performed that revealed Schistosoma mansoni worm eggs as an unexpected diagnostic finding. Serological tests for specific antibodies and parasitological egg detection in the stool confirmed the diagnosis. After only temporary response to a short-term and low-dose treatment with praziquantel, a 3-day high-dose (40 mg/kg body weight) treatment with praziquantel finally led to long-lasting symptom relief. © 2016, Springer-Verlag Berlin Heidelberg.

Author Keywords

Recurrence, Schistosoma mansoni Biopsy, liver Serologic tests Hematochezia Schistosomiasis

Index Keywords

Nigeria parasitology Germany differential diagnosis Diagnosis, Differential refugee Therapeutics Anus Diseases rectum hemorrhage Anthelmintics optimal drug dose low drug dose Transaminases complication human Refugees anthelmintic agent Pelvic Pain Liver Diseases aminotransferase liver function test Humans Hemorrhage male case report Schistosoma mansoni Liver Function Tests liver biopsy schistosomiasis mansoni therapy Article worm egg blood adult serology praziquantel
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84966696748&doi=10.1007%2fs00108-016-0052-8&partnerID=40&md5=307879031c2ffdd2c4c7f3d22bd885a9
DOI: 10.1007/s00108-016-0052-8
ISSN: 00209554
Original Language: German