Xenotransplantation
Volume 23, Issue 4, 2016, Pages 269-278

Acceptance of organ xenotransplantation among Latin American immigrants resident in the United States (Article)

Ríos A.* , López-Navas A.I. , Martínez-Alarcón L. , Ramis G. , Hernández A.M. , Ayala M.A. , Garrido G. , Ramírez P. , Parrilla P.
  • a International Collaborative Donor Project (“Proyecto Colaborativo Internacional Donante”), Murcia, Spain, Regional Transplant Center, Consejería de Sanidad, Murcia Health Service, Murcia, Spain, Department of Surgery, Faculty of Medicine, University of Murcia, Murcia, Spain, Surgery Service, Virgen de la Arrixaca University Hospital (IMIB), Murcia Health Service, Murcia, Spain
  • b International Collaborative Donor Project (“Proyecto Colaborativo Internacional Donante”), Murcia, Spain, Regional Transplant Center, Consejería de Sanidad, Murcia Health Service, Murcia, Spain, Department of Psychology, UCAM, San Antonio Catholic University, Murcia, Spain
  • c International Collaborative Donor Project (“Proyecto Colaborativo Internacional Donante”), Murcia, Spain, Regional Transplant Center, Consejería de Sanidad, Murcia Health Service, Murcia, Spain, Surgery Service, Virgen de la Arrixaca University Hospital (IMIB), Murcia Health Service, Murcia, Spain
  • d Faculty of Veterinary, University of Murcia, Murcia, Spain
  • e Endocrinology and Nutrition Service, Unidad de Docencia y Formación Continuada, Servicio Murciano de Salud, Virgen de la Arrixaca University Hospital, Murcia, Spain
  • f Hospital Regional de Alta Especialidad del Bajío, León, Guanajuato, Mexico, HGSZ No 10 del Instituto Mexicano del Seguro Social Delegación Guanajuato, Guanajuato, Mexico
  • g Organización Nacional de Trasplantes, Madrid, Spain
  • h Regional Transplant Center, Consejería de Sanidad, Murcia Health Service, Murcia, Spain, Department of Surgery, Faculty of Medicine, University of Murcia, Murcia, Spain, Surgery Service, Virgen de la Arrixaca University Hospital (IMIB), Murcia Health Service, Murcia, Spain
  • i Department of Surgery, Faculty of Medicine, University of Murcia, Murcia, Spain, Surgery Service, Virgen de la Arrixaca University Hospital (IMIB), Murcia Health Service, Murcia, Spain

Abstract

Background: Making xenotransplantation socially acceptable is the first step in working toward the promotion of this potential therapy option for providing transplant organs. Objective: To analyze the attitude toward xenotransplantation among the Latin American population resident in Florida (the USA), and to determine the variables affecting this attitude. Methods: A sample of Latin American residents in the state of Florida was randomized and stratified according to nationality, age, and sex (n = 1524). Attitude was assessed using a validated questionnaire (PCID—XenoTx Rios) which was self-completed anonymously. Statistical analysis: descriptive analysis, Student's t-test, the chi-square test, and a logistic regression analysis. Results: The questionnaire completion rate was 95% (n = 1450). If it was assumed that xenotransplanted organs functioned as well as human ones, 10% (n = 147) would be in favor, 73% (n = 1092) against, and 17% (n = 246) undecided. If the results were worse, only 2% (n = 35) would be in favor. This favorable attitude was related to country of origin (Honduras and Guatemala; P < 0.001); age (P < 0.001); sex (women; P < 0.001); marital status (married; P < 0.001); descendents (yes; P < 0.001); level of formal education (secondary education and university; P < 0.001); participation in voluntary prosocial activities (yes; P < 0.001); having spoken about donation and transplantation within the family (yes; P < 0.001); a partner's favorable attitude toward transplantation (P = 0.040); religion (catholic; P < 0.001); knowing the attitude of one's religion toward donation (yes; P < 0.001); previous experience of donation and/or transplantation (yes; P < 0.001); a belief that one might need a transplant in the future (yes; P < 0.001); and a favorable attitude toward human donation (yes; P < 0.001). The following were associated with attitude in the multivariate analysis: age (≥40 yrs; OR = 1.152); marital status (married; OR = 500); prosocial activities (yes, I participate in them; OR = 9.196. No, but I would like to; OR = 332.538); religion (catholic; OR = 2000); attitude toward deceased organ donation (in favor; OR = 2000); and previous experience of donation and/or transplantation (yes; OR = 500). Conclusions: The attitude of Latin Americans resident in Florida toward xenotransplantation is very negative, and is determined by many psychosocial factors, mainly related to their prior attitude toward the different kinds of human organ donation. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Author Keywords

Latin American Attitude psychosocial factors general population Xenotransplantation Immigration USA Family

Index Keywords

educational status immigrant social acceptance Guatemala progeny human sex difference priority journal Aged religion organ donor marriage United States xenotransplantation attitude Hispanic Adolescent male female Honduras questionnaire Article adult age distribution social behavior
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84982221113&doi=10.1111%2fxen.12250&partnerID=40&md5=fd0bff08c9b43fd1051a51e136c2f5ab
DOI: 10.1111/xen.12250
ISSN: 0908665X
Cited by: 9
Original Language: English