International Journal of Tuberculosis and Lung Disease
Volume 20, Issue 6, 2016, Pages 771-777

The diabetes-tuberculosis co-epidemic: The role of international migration (Article)

Caraffa E.* , Sañe Schepisi M. , Gualano G. , Parracino M.P. , Rianda A. , Corpolongo A. , Pinnetti C. , Galati V. , Carballo M. , Ippolito G. , Palmieri F. , Girardi E.
  • a Department of Epidemiology and Preclinical Research, National Institute for Infectious Diseases L Spallanzani IRCCS, Via Portuense 292, Rome, 00149, Italy
  • b Department of Epidemiology and Preclinical Research, National Institute for Infectious Diseases L Spallanzani IRCCS, Via Portuense 292, Rome, 00149, Italy
  • c Clinical Department, National Institute for Infectious Diseases L Spallanzani, Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS), Rome, Italy
  • d Department of Epidemiology and Preclinical Research, National Institute for Infectious Diseases L Spallanzani IRCCS, Via Portuense 292, Rome, 00149, Italy
  • e Clinical Department, National Institute for Infectious Diseases L Spallanzani, Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS), Rome, Italy
  • f Clinical Department, National Institute for Infectious Diseases L Spallanzani, Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS), Rome, Italy
  • g Clinical Department, National Institute for Infectious Diseases L Spallanzani, Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS), Rome, Italy
  • h Clinical Department, National Institute for Infectious Diseases L Spallanzani, Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS), Rome, Italy
  • i International Centre for Migration, Health and Development, Geneva, Switzerland
  • j Office of the Scientific Dir., National Institute for Infectious Diseases L Spallanzani IRCCS, Rome, Italy
  • k Clinical Department, National Institute for Infectious Diseases L Spallanzani, Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS), Rome, Italy
  • l Department of Epidemiology and Preclinical Research, National Institute for Infectious Diseases L Spallanzani IRCCS, Via Portuense 292, Rome, 00149, Italy

Abstract

ETTING: A tuberculosis (TB) referral centre in Rome, Italy. OBJECTIVE : To identify demographic and epidemiological characteristics associated with diabetes mellitus (DM) among patients with TB and to compare the clinical presentation of TB and TB-DM in the light of the growing worldwide burden of DM. DESIGN: We performed a retrospective study of TB cases diagnosed from 2007 to 2012. RESULT S : Among 971 TB patients, 723 were foreignborn and 63 (6.5%) had DM. DM prevalence was 12.7% (8/63) among those born in countries with DM prevalence 78%, 4.7% (31/660) among patients from countries with DM prevalence ,8% and 9.7% among Italian patients (24/248). In multivariable analysis, DM was independently associated with older age, and with being born in countries other than Italy, compared to Italians; this latter association was stronger in older patients. DM patients were also significantly more likely to be male and less likely to test positive for the human immunodeficiency virus. The presence of cavities was significantly associated with DM. CONCLUS IONS : As individuals born in high TB incidence and high DM prevalence countries emerge as a vulnerable population, greater attention to bidirectional low-cost screening in people from these countries is needed. © 2016 The Union.

Author Keywords

Foreign-born DM-TB comorbidity Bidirectional screening

Index Keywords

extrapulmonary tuberculosis Human immunodeficiency virus infection mass screening insulin dependent diabetes mellitus demography non insulin dependent diabetes mellitus clinical feature Diabetes Mellitus, Type 2 human middle aged birthplace aging controlled study priority journal Aged HIV Seropositivity ethnology epidemiological data diabetic patient Epidemics Young Adult Humans lung tuberculosis tuberculostatic agent Adolescent male Italian (citizen) female Aged, 80 and over tuberculosis very elderly dental caries prevalence Incidence Article epidemic Retrospective Studies major clinical study adult microbiological examination migration Emigration and Immigration Italy retrospective study sex
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84966460651&doi=10.5588%2fijtld.15.0295&partnerID=40&md5=5e07fd2fc2d0c3729ab02f6f96516d8f
DOI: 10.5588/ijtld.15.0295
ISSN: 10273719
Cited by: 5
Original Language: English