Human Vaccines and Immunotherapeutics
Volume 12, Issue 5, 2016, Pages 1141-1148

Hepatitis B birth dose vaccination rates among children in Beijing: A comparison of local residents and first and second generation migrants (Article) (Open Access)

Chen R. , Li Y. , Wangen K.R. , Nicholas S. , Maitland E. , Wang J.*
  • a Center for Health Economic Experiments and Public Policy, School of Public Health, Shandong University, Jinan, Shandong, China
  • b School of Humanity and Social Science, Shandong University of TCM, Jinan, Shandong, China
  • c Department of Health Management and Health Economics, University of Oslo, Oslo, Norway
  • d School of Management-School of Commerce, Tianjin Normal University, Tianjin, China, School of International Business, Beijing Foreign Studies University, Haidian, Beijing, China, Research Institute of International Strategies, Guangdong University of Foreign Studies, Guangzhou, China, Newcastle Business School, University of Newcastle, Newcastle, NSW, Australia
  • e UNSW Business School, UNSW, Sydney, NSW, Australia
  • f Center for Health Economic Experiments and Public Policy, School of Public Health, Shandong University, Jinan, Shandong, China

Abstract

Providing hepatitis B vaccine to all neonates within 24 hours of birth (Timely Birth Dose, TBD) is the key preventative measure to control perinatal hepatitis B virus infection. Previous Chinese studies of TBD only differentiated between migrant and non-migrant (local-born generation-LG) children. Our study is the first to stratify migrants in Beijing into first generation migrants (FGM) and second generation migrants (SGM). Based on a questionnaire survey of 2682 people in 3 Beijing villages, we identified 283 children aged 0–15 years, from 246 households, who were eligible for a TBD. Multinomial logistic regression and statistical analyses were used to examine factors explaining TBD rates for LG, FGM and SGM children. Surprisingly, the TBD for LG Beijing children was not significantly different from migrant children. But after stratifying migrant children into FGM and SGM, revealed significant TBD differences were revealed across LG, FGM and SGM according to domicile (p-value < 0.001, OR = 3.24), first vaccination covered by government policy (p-value < 0.05, OR = 3.24), mother's knowledge of hepatitis B (p-value < 0.05, OR = 1.01) and the government's HBV policy environment (p-value < 0.05, OR = 2.338). Birthplace (p-value = 0.002, OR = 6.21) and better policy environments (p-value = 0.01, OR = 2.80) were associated with higher TBD rate for LG and SGM children. Compared with FGM children, SGM had a significantly poorer TBD rate (Fisher exact test of chi-square = 0.013). We identified SGM as a special risk group; proposed Hukou reform to improve SGM TBD; and called for Beijing health authorities to match TBD rates in other provinces, especially by improving practices by health authorities and knowledge of parents. © 2016 Taylor & Francis.

Author Keywords

Vaccination Migrant Children Hepatitis B second generation migrant timely birth dose policy inequity first generation migrant

Index Keywords

education Parents China educational status health care planning health survey human birthplace statistics and numerical data economic aspect comparative study sensitivity analysis Logistic Models Hepatitis B virus family size procedures resident Family Characteristics Surveys and Questionnaires school child migrant cross-sectional study Humans virology Adolescent Infant, Newborn male parent female preschool child Infant Beijing Child, Preschool newborn questionnaire pregnancy immunology patient education Article legislation and jurisprudence Hepatitis B Vaccines major clinical study migration hepatitis B vaccine Perinatal Care statistical model Transients and Migrants vaccination hepatitis B immunization Healthcare Disparities health care disparity Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962061534&doi=10.1080%2f21645515.2015.1131370&partnerID=40&md5=cdf9913df1d12e6f74c92b2bd158bda6
DOI: 10.1080/21645515.2015.1131370
ISSN: 21645515
Cited by: 1
Original Language: English