Clinical Pediatrics
Volume 46, Issue 4, 2007, Pages 349-355

Congenital rubella syndrome in a child born to Liberian refugees: Clinical and public health perspectives (Article)

Plotinsky R.N. , Talbot E.A.* , Kellenberg J.E. , Reef S.E. , Buseman S.K. , Wright K.D. , Modlin J.F.
  • a Division of Public Health Services, Department of Health and Human Services, Concord, NH, United States, Epidemic Intelligence Service, Office of Workforce and Career Development, Atlanta, GA, United States
  • b Division of Public Health Services, Department of Health and Human Services, Concord, NH, United States, Dartmouth Medical School, Hanover, NH, United States, Dartmouth Hitchcock Medical Center, Lebanon, NH, United States, 29 Hazen Dr, Concord, NH 03301, United States
  • c Manchester Health Department, Manchester, NH, United States
  • d National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA, United States
  • e Manchester Health Department, Manchester, NH, United States
  • f Dartmouth Hitchcock Medical Center, Lebanon, NH, United States
  • g Dartmouth Medical School, Hanover, NH, United States, Dartmouth Hitchcock Medical Center, Lebanon, NH, United States

Abstract

We describe a case of congenital rubella syndrome with typical stigmata in an infant born in New Hampshire to Liberian refugees. The infant's clinical specimens were tested for rubella. Rubella immunity status was sought for contacts. The infant's specimen cultures grew wild-type rubella virus; serum immunoglobulin M and G were positive. Eighteen of 20 contacts were rubella-immune. Family's transit history, mother's vaccination history, and infant's estimated gestational age supported congenital infection acquired overseas. Clinicians should maintain vigilance for congenital rubella syndrome in infants with relevant stigmata, particularly those whose mothers are from countries with nonexistent or recently implemented rubella vaccination programs. © 2007 Sage Publications.

Author Keywords

congenital rubella syndrome Vaccination Refugee

Index Keywords

immunoglobulin blood level refugee Rubella virus congestive heart failure human clinical assessment Refugees arthralgia virus immunity heart left right shunt New Hampshire heart murmur virus culture wild type lymphadenopathy United States Rubella Syndrome, Congenital congenital rubella syndrome Humans hearing impairment antibody detection African Continental Ancestry Group Infant, Newborn case report female Infant enzyme linked immunosorbent assay Liberia Article Contact Tracing patent ductus arteriosus fever maculopapular rash pneumonia childbirth immunoglobulin G enzyme immunoassay gestational age immunoglobulin M rubella vaccine public health
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-34247256812&doi=10.1177%2f0009922806293915&partnerID=40&md5=6f166090e84fe919db707155236e828e
DOI: 10.1177/0009922806293915
ISSN: 00099228
Cited by: 7
Original Language: English