Annals of Internal Medicine
Volume 146, Issue 1, 2007, Pages 20-24

Susceptibility to measles, mumps, and rubella in newly arrived adult immigrants and refugees (Article)

Greenaway C.* , Dongier P. , Boivin J.-F. , Tapiero B. , Miller M. , Schwartzman K.
  • a Sir Mortimer B. Davis Jewish General Hospital, Côte-des-Neiges Local Community Health Center, McGill University, Montreal, QC, Canada, Division of Infectious Diseases, SMBD-Jewish General Hospital, 3755 Côte Ste. Catherine Road, Montréal, QC H3T 1E2, Canada
  • b Sir Mortimer B. Davis Jewish General Hospital, Côte-des-Neiges Local Community Health Center, McGill University, Montreal, QC, Canada, Clinique Santé Acceuil, CLSC Côte-des-Neiges, 5700 Chemin de la Côte-des-Neiges, Montréal, QC H3T 2A6, Canada
  • c Sir Mortimer B. Davis Jewish General Hospital, Côte-des-Neiges Local Community Health Center, McGill University, Montreal, QC, Canada, Epidemiology and Biostatistics, McGill University, 1020 Pine West, Montréal, QC H3A 1A2, Canada
  • d Sir Mortimer B. Davis Jewish General Hospital, Côte-des-Neiges Local Community Health Center, McGill University, Montreal, QC, Canada, CHU Mère-Enfant Sainte-Justine, Service de Maladies Infectieuses, 3175 Cote Ste. Catherine Road, Montréal, QC H3T 1C5, Canada
  • e Sir Mortimer B. Davis Jewish General Hospital, Côte-des-Neiges Local Community Health Center, McGill University, Montreal, QC, Canada, Infectious Diseases, SMBD-Jewish General Hospital, 3755 Côte Ste. Catherine Road, Montréal, QC H3T 1E2, Canada
  • f Sir Mortimer B. Davis Jewish General Hospital, Côte-des-Neiges Local Community Health Center, McGill University, Montreal, QC, Canada, Respiratory Epidemiology Unit, McGill University, Montréal Chest Institute, 3650 St. Urbain, Montréal, QC H2X 2P4, Canada

Abstract

Background: Despite effective vaccination programs for measles, mumps, and rubella in the United States and Canada, outbreaks continue to occur in susceptible subgroups, such as foreign-born persons. Objective: To determine the susceptibility of newly arrived immigrants and refugees to measles, mumps, and rubella. Design: Seroprevalence study. Setting: Two hospitals and three community clinics in Montreal, Quebec, Canada. Patients: 1480 adult immigrants and refugees who were recruited from October 2002 to December 2004. Measurements: Sociodemographic and clinical data and serology for measles, mumps, and rubella. Results: Thirty-six percent (range, 22% to 54%) of the study population was nonimmune to at least 1 of the 3 diseases. This proportion varied by age, sex, and region of origin. In multivariate analysis and after adjustment for region of origin, age, and socioeconomic factors, immigrant women had higher odds (odds ratio, 2.1) of being immune to measles (95% CI, 1.2 to 3.8) and an odds ratio of 1.7 of being nonimmune to rubella (CI, 1.2 to 2.6) compared with immigrant men. Limitations: The results from the community-based convenience sample of immigrants may not be generalizable to all immigrant populations. Conclusions: Many new immigrants and refugees, particularly women, are susceptible to measles, mumps, or rubella and may benefit from targeted vaccination programs. © 2007 American College of Physicians.

Author Keywords

[No Keywords available]

Index Keywords

statistical analysis immigrant refugee Antibodies, Viral demography sex ratio Disease Susceptibility human epidemiology Refugees middle aged priority journal Aged Humans Adolescent male Canada female Aged, 80 and over geographic origin questionnaire immunology Article blood major clinical study adult migration disease predisposition mumps age distribution Emigration and Immigration rubella vaccination seroprevalence Seroepidemiologic Studies measles infection sensitivity virus antibody
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-33846915749&doi=10.7326%2f0003-4819-146-1-200701020-00005&partnerID=40&md5=096e54d7055e0ebdb52e7fd5a2063ae6
DOI: 10.7326/0003-4819-146-1-200701020-00005
ISSN: 00034819
Cited by: 35
Original Language: English