Emerging Infectious Diseases
Volume 24, Issue 11, 2018, Pages 2084-2086

Fatal case of diphtheria and risk for reemergence, Singapore (Article) (Open Access)

Lai Y.* , Purnima P. , Ho M. , Ang M. , Deepak R.N. , Chew K.L. , Vasoo S. , Capulong D.F. , Lee V.
  • a Ministry of Health, Singapore, Communicable Diseases Division, Ministry of Health, Singapore
  • b Khoo Teck Puat Hospital, Singapore
  • c Ministry of Health, Singapore
  • d Ministry of Health, Singapore, National Public Health Laboratory, Singapore
  • e Khoo Teck Puat Hospital, Singapore
  • f National University Hospital, Singapore
  • g Tan Tock Seng Hospital, Singapore
  • h Tan Tock Seng Hospital, Singapore
  • i Ministry of Health, Singapore

Abstract

We report a fatal autochthonous diphtheria case in a migrant worker in Singapore. This case highlights the risk for individual cases in undervaccinated subpopulations, despite high vaccination coverage in the general population. Prompt implementation of public health measures and maintaining immunization coverage are critical to prevent reemergence of diphtheria. © 2018, Centers for Disease Control and Prevention (CDC). All rights reserved.

Author Keywords

[No Keywords available]

Index Keywords

transmission human risk assessment travel Young Adult Humans male case report clinical article gene contact examination erythromycin polymerase chain reaction immunology isolation and purification Article Communicable Diseases, Emerging Contact Tracing Disease Notification Corynebacterium diphtheriae Fatal Outcome communicable disease adult bacterial vaccine fatality suppuration Phylogeny edema tracheostomy diphtheria vaccine diphtheria toxoid gene sequence vaccination coverage computer assisted tomography Singapore clarithromycin odynophagia hypoxia airway obstruction Bacterial Vaccines multilocus sequence typing vaccination disease re-emergence Bangladesh single nucleotide polymorphism immunization diphtheria diphtheria antibody hemoptysis public health
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055072900&doi=10.3201%2feid2411.180198&partnerID=40&md5=b6cb1d93bf4e69e30d69c58d8f3203bc
DOI: 10.3201/eid2411.180198
ISSN: 10806040
Original Language: English