Stroke
Volume 37, Issue 8, 2006, Pages 1986-1990

Estimation of the risk of stroke in black populations in Barbados and South London (Article) (Open Access)

Wolfe C.D.A.* , Corbin D.O.C. , Smeeton N.C. , Gay G.H.E. , Rudd A.G. , Hennis A.J. , Wilks R.J. , Fraser H.S.
  • a King's College London, Division of Health and Social Care, London, United Kingdom, Department of Public Health Medicine, King's College London, Division of Health and Social Care, 42 Weston Street, London SE1 3QD, United Kingdom
  • b Chronic Disease Research Centre/Tropical Medicine Research Institute, School of Clinical Medicine and Research, University of the West Indies, Barbados
  • c King's College London, Division of Health and Social Care, London, United Kingdom
  • d Chronic Disease Research Centre/Tropical Medicine Research Institute, School of Clinical Medicine and Research, University of the West Indies, Barbados
  • e Guy's and St. Thomas' Foundation Trust, St. Thomas' Hospital, London, United Kingdom
  • f Chronic Disease Research Centre/Tropical Medicine Research Institute, School of Clinical Medicine and Research, University of the West Indies, Barbados
  • g Tropical Medicine Research Institute, School of Clinical Medicine and Research, University of the West Indies, Jamaica
  • h Chronic Disease Research Centre/Tropical Medicine Research Institute, School of Clinical Medicine and Research, University of the West Indies, Barbados

Abstract

BACKGROUND AND PURPOSE - The incidence of stroke in black populations is a public health issue, but how risk varies between black communities is unclear. METHODS - Population-based registers in South London (SLSR) and Barbados (Barbados Register of Strokes [BROS]). Stroke incidence estimated by age group, gender and stroke subtype from January 1995 to December 2002 (SLSR), and October 2001 to September 2003 (BROS). Incidence rate ratios [IRR] estimated adjusting for age and sex. RESULTS - Two hundred and seventy-one cases registered in SLSR and 628 cases in BROS. Average age of stroke was 66.1 years (SD 13.7) in SLSR and 71.5 years (SD 14.9) in BROS (P<0.001). The incidence rate/1000 population in SLSR was 1.61 (European adjusted; 95% CI, 1.41 to 1.81) and 1.08 (world adjusted; 95% CI, 0.95 to 1.21). For Barbados incidence rates were 1.29 (European adjusted; 95% CI, 1.19 to1.39) and 0.85 (world adjusted; 95% CI, 0.78 to 0.92). Overall IRR for SLSR: BROS adjusted for age and sex was 1.26 (95% CI, 1.09 to 1.46). Statistically significant subtype differences included total anterior cerebral infarction (IRR, 1.82; 95% CI, 1.23 to 2.69), posterior cerebral infarction (IRR, 2.12; 95% CI, 1.28 to 3.53), primary intracerebral hemorrhage (IRR, 1.56; 95% CI, 1.03 to 2.35) and subarachnoid hemorrhage (IRR, 5.04; 95% CI, 2.54 to 9.97). CONCLUSIONS - The risk of stroke in black Caribbeans is higher in South London than Barbados, and particularly so for specific stroke subtypes. The risk in Barbados approaches that in the white population in South London and strokes occur at an older age. Whether environmental factors mediate these differences in migrant populations requires further study. © 2006 American Heart Association, Inc.

Author Keywords

Incidence Stroke Ethnicity

Index Keywords

Negro Stroke cerebrovascular accident population brain hemorrhage Caucasian London human risk assessment community middle aged statistics controlled study priority journal comparative study Aged Central America subarachnoid hemorrhage brain infarction Cerebral Hemorrhage ethnology Cerebral Infarction statistical significance Barbados Confidence interval Humans classification Adolescent African Continental Ancestry Group Infant, Newborn male environmental factor female newborn Caribbean Region time series analysis Incidence Article major clinical study adult gender age European Continental Ancestry Group United Kingdom age distribution sex public health
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-33747155341&doi=10.1161%2f01.STR.0000230578.10937.a6&partnerID=40&md5=5aa4282566e1f9a66f4550225d132ae2
DOI: 10.1161/01.STR.0000230578.10937.a6
ISSN: 00392499
Cited by: 25
Original Language: English