New Microbiologica
Volume 29, Issue 3, 2006, Pages 207-209

Analysis of the shift of the transmission pattern for hepatitis C in a community in Central Italy (Article)

Petti S. , Divizia M.* , Donia D. , D'Arca A.S. , Tarsitani G. , Fabi G. , Panà A.
  • a University La Sapienza, Department of Public Health Sciences G. Sanarelli, Rome, Italy
  • b University Tor Vergata, Department of Public Health and Cellular Biology, Rome, Italy, Dept. of Public Health and Cellular Biology, University of Rome Tor Vergata, Rome, Italy
  • c University Tor Vergata, Department of Public Health and Cellular Biology, Rome, Italy
  • d University La Sapienza, Department of Public Health Sciences G. Sanarelli, Rome, Italy
  • e University La Sapienza, Department of Public Health Sciences G. Sanarelli, Rome, Italy
  • f [Affiliation not available]
  • g [Affiliation not available]

Abstract

Anti-HCV and HCV-RNA prevalence among adults from an isolated Central Italian community were 16.3% and 9.0%; 3.0%, 2.3% among 25-to-49-year-olds, 27.6%, 14.7% among older subjects. 1b genotype prevailed (88.5%). 1a, 1a/1b, 4 were also isolated. Seropositivity was associated with age >50 years, public dental health care, glass syringe use, surgical interventions. The transmission pattern seems to be shifting from that typical of Southern Italy (high prevalence, particularly in the elderly, 1b genotype predominant, various routes of transmission involved, cohort effect), to that typical of Europe (lower prevalence, particularly among younger adults, other genotypes involved, association with intravenous drug use and immigrants).

Author Keywords

Hepatitis C virus (HCV) HCV risk factors Public health care HCV transmission dentistry

Index Keywords

genetics genotype chemistry human epidemiology middle aged Hepatitis C virus RNA, Viral Humans virology virus RNA immunology Article disease transmission blood adult hepatitis C antibody Immunoenzyme Techniques Italy Hepatitis C Antibodies Seroepidemiologic Studies enzyme immunoassay Hepacivirus hepatitis C
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-33749175965&partnerID=40&md5=397df9703b1c318d155a8ce016b94436
ISSN: 11217138
Cited by: 4
Original Language: English