Nederlands Tijdschrift voor Geneeskunde
Volume 150, Issue 9, 2006, Pages 495-499
Severe vitamin-D deficiency in more than half of the immigrant pregnant women of non-Western origin and their newborns [Ernstige vitamine D-deficiëntie bij ruim de helft van de niet-westerse allochtone zwangeren en hun pasgeborenen] (Article)
Wielders J.P.M.* ,
Van Dormaël P.D. ,
Eskes P.F. ,
Duk M.J.
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a
Afd. Klinische Chemie, Meander Medisch Centrum, Utrechtseweg 160, 3818 ES Amersfoort, Netherlands
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b
Afd. Obstetrie en Gynaecologie, Meander Medisch Centrum, Utrechtseweg 160, 3818 ES Amersfoort, Netherlands
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c
Afd. Kindergeneeskunde, Meander Medisch Centrum, Utrechtseweg 160, 3818 ES Amersfoort, Netherlands
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d
Afd. Obstetrie en Gynaecologie, Meander Medisch Centrum, Utrechtseweg 160, 3818 ES Amersfoort, Netherlands
Abstract
Objective. To determine the prevalence of vitamin-D deficiency in pregnant women and their newborns. Design. Descriptive. Method. During the period of one year (April 2004-April 2005) 545 pregnant women of Dutch/European origin and 131 pregnant women of non-Western origin (mainly Turkish and Moroccan) were studied during their 10th and/or 30th week of pregnancy for calcidiol (vitamin-D) and calcium levels. The study took place in the Amersfoort region in the center of the Netherlands. In addition, cord blood samples were taken for vitamin-D and calcium levels from the 442 and 81 Dutch/European and non-Western newborns respectively. Results. A severe deficiency was found (calcidiol < 20 nmol/l) in 55% of non-European women compared to 5% of Dutch/West-European women. From the cord blood samples, a severe vitamin-D deficiency (calcidiol < 13 nmol/l) was found in 54% of the newborns of non-European origin compared to 6% of the Dutch/West-European newborns. Vitamin-D concentrations in pregnant women at term were strongly correlated to the concentrations in the newborns' cord blood (R = 0.84). The calcium levels of pregnant women and newborns did not differ significantly between both population groups. Conclusion. More than half of the non-European pregnant women and their newborns had a severe vitamin-D deficiency. Screening for vitamin D deficiency and adequate suppletion for this risk group appears to be necessary. The causes and consequences of vitamin-D deficiency in pregnancy are discussed.
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-33644908765&partnerID=40&md5=8bcba128d02346801ce8e3da1275085e
ISSN: 00282162
Cited by: 23
Original Language: Dutch