Chinese Journal of Clinical Rehabilitation
Volume 9, Issue 15, 2005, Pages 36-37

Effect of ginkgo-leaf tablets on the pulmonary ventilation function in young migrants at high altitude (Article)

Wang W.* , Wang Y.-H. , Zhang X.-Z. , Zhang F. , Ha Z.-D. , Cui J.-H. , Ma Y. , Xing G.-X.
  • a Institute of Altitude Disease, 18 Hospital of Chinese PLA, Yecheng 844900 Xinjiang Uygur, China
  • b Institute of Altitude Disease, 18 Hospital of Chinese PLA, Yecheng 844900 Xinjiang Uygur, China
  • c Institute of Altitude Disease, 18 Hospital of Chinese PLA, Yecheng 844900 Xinjiang Uygur, China
  • d Institute of Altitude Disease, 18 Hospital of Chinese PLA, Yecheng 844900 Xinjiang Uygur, China
  • e Institute of Altitude Disease, 18 Hospital of Chinese PLA, Yecheng 844900 Xinjiang Uygur, China
  • f Institute of Altitude Disease, 18 Hospital of Chinese PLA, Yecheng 844900 Xinjiang Uygur, China
  • g Institute of Altitude Disease, 18 Hospital of Chinese PLA, Yecheng 844900 Xinjiang Uygur, China
  • h Institute of Altitude Disease, 18 Hospital of Chinese PLA, Yecheng 844900 Xinjiang Uygur, China

Abstract

Aim: To study the influence of ginkgo-leaf tablets on the pulmonary ventilation function of young migrants at high altitude, so as to find out drugs that can ameliorate the pulmonary ventilation function at high altitude. Methods: Twenty youths, who had been living at 3 700 m altitude for 6 months, were randomly divided into control group(n = 10) and study group (n = 10). Subjects in the control group and study group were treated with oral medication of self-made Chaomian capsule and ginkgo-leaf tablets respectively, two pills for each time, twice a day. They were asked to do the sitting cycling with the bicycle ergometer about 60 r per minutes, the initial load power was 25 W, and the resistance was progressively increased by 25 W every 3 minutes up to exhaustion before and 15 days after medication for 15 days, their minute ventilation volume and the oxygen saturation at 225 W of each subjects were calculated. Results: Ventilation volume and oxygen saturation after medication in the study group [(37.96 ± 3.87) L per minute, (78.40 ± 1.96)%] were obviously lower and higher than those before medication[(32.13 ± 3.56) L per minute, (75.60 ± 1.34)%] (t = 3.51, 3.73, P < 0.01) and those in the control group(t = 3.35, 3.82, P < 0.01) respectively. Conclusion: Medication of ginkgo-leaf tablets can obviously improve the pulmonary ventilation and work efficiency of young migrants at high altitude.

Author Keywords

[No Keywords available]

Index Keywords

chaomian Ginkgo biloba lung ventilation Ginkgo biloba extract Chinese drug controlled clinical trial clinical trial human altitude disease oxygen saturation work controlled study randomized controlled trial drug efficacy drug capsule Chinese medicine unclassified drug clinical article tablet formulation bicycle ergometry Article adult migration drug effect
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-27644554001&partnerID=40&md5=91c4324c9ac2a0658e0da303351c0f19
ISSN: 16715926
Cited by: 2
Original Language: Chinese