Bulletin of the World Health Organization
Volume 92, Issue 12, 2014, Pages 881-893

Post-licensure deployment of oral cholera vaccines: A systematic review [Déploiement après homologation des vaccins oraux contre le choléra: Une revue systématique] (Review) (Open Access)

Martin S. , Lopez A.L. , Bellos A. , Deen J.* , Ali M. , Alberti K. , Anh D.D. , Costa A. , Grais R.F. , Legros D. , Luquero F.J. , Ghai M.B. , Perea W. , Sack D.A.
  • a Pandemic and Epidemic Diseases Department, World Health Organization, Geneva, Switzerland
  • b University of the Philippines Manila-National Institutes of Health, Manila, Philippines
  • c Pandemic and Epidemic Diseases Department, World Health Organization, Geneva, Switzerland
  • d University of the Philippines Manila-National Institutes of Health, Manila, Philippines
  • e Delivering Oral Vaccine Effectively (DOVE), Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, United States
  • f United Nations Plaza, New York, United States
  • g National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam
  • h Pandemic and Epidemic Diseases Department, World Health Organization, Geneva, Switzerland
  • i Epicentre, Paris, France
  • j Pandemic and Epidemic Diseases Department, World Health Organization, Geneva, Switzerland
  • k Epicentre, Paris, France
  • l Pandemic and Epidemic Diseases Department, World Health Organization, Geneva, Switzerland
  • m Pandemic and Epidemic Diseases Department, World Health Organization, Geneva, Switzerland
  • n Delivering Oral Vaccine Effectively (DOVE), Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, United States

Abstract

Objective To describe and analyse the characteristics of oral cholera vaccination campaigns; including location, target population, logistics, vaccine coverage and delivery costs.Methods We searched PubMed, the World Health Organization (WHO) website and the Cochrane database with no date or language restrictions. We contacted public health personnel, experts in the field and in ministries of health and did targeted web searches.Findings A total of 33 documents were included in the analysis. One country, Viet Nam, incorporates oral cholera vaccination into its public health programme and has administered approximately 10.9 million vaccine doses between 1997 and 2012. In addition, over 3 million doses of the two WHO pre-qualified oral cholera vaccines have been administered in more than 16 campaigns around the world between 1997 and 2014. These campaigns have either been pre-emptive or reactive and have taken place under diverse conditions, such as in refugee camps or natural disasters. Estimated two-dose coverage ranged from 46 to 88% of the target population. Approximate delivery cost per fully immunized person ranged from 0.11-3.99 United States dollars.Conclusion Experience with oral cholera vaccination campaigns continues to increase. Public health officials may draw on this experience and conduct oral cholera vaccination campaigns more frequently. © 2014, World Health Organization, All rights reserved.

Author Keywords

[No Keywords available]

Index Keywords

global health Vietnam Viet Nam world health organization preventive health service oral drug administration Administration, Oral Immunization Programs Public Health Practice economics public health service Cholera Vaccines cholera vaccine health cholera human Humans
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84914096816&doi=10.2471%2fBLT.14.139949&partnerID=40&md5=4146cedeb56b25d5b2c55852e5fc35a2
DOI: 10.2471/BLT.14.139949
ISSN: 00429686
Cited by: 41
Original Language: English