American Journal of Tropical Medicine and Hygiene
Volume 87, Issue 2, 2012, Pages 242-250

Insecticide-treated plastic sheeting for emergency malaria prevention and shelter among displaced populations: An observational cohort study in a refugee setting in Sierra Leone (Article) (Open Access)

Burns M.* , Rowland M. , N'Guessan R. , Carneiro I. , Beeche A. , Ruiz S.S. , Kamara S. , Takken W. , Carnevale P. , Allan R.
  • a Department of Entomology, Wageningen University, Radix Building 107, Droevendaalsesteeg 1, 6708 PB, Wageningen, Netherlands
  • b Department of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
  • c Department of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
  • d Department of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
  • e International Development Research Centre, Ottawa, ON, Canada
  • f MENTOR Initiative, Shaw House, Pegler Way, Crawley, United Kingdom
  • g National Malaria Control Programme, Freetown, Sierra Leone
  • h Department of Entomology, Wageningen University, Radix Building 107, Droevendaalsesteeg 1, 6708 PB, Wageningen, Netherlands
  • i Laboratoire de Lutte contre les Insectes Nuisibles (LIN), Institut de Recherche Pour le Developpement (IRD), Montpellier, France
  • j MENTOR Initiative, Shaw House, Pegler Way, Crawley, United Kingdom

Abstract

A double-blind phase III malaria prevention trial was conducted in two refugee camps using premanufactured insecticide-treated plastic sheeting (ITPS) or untreated polyethylene sheeting (UPS) randomly deployed to defined sectors of each camp. In Largo camp the ITPS or UPS was attached to inner walls and ceilings of shelters, whereas in Tobanda the ITPS or UPS was used to line only the ceiling and roof. In Largo the Plasmodium falciparum incidence rate in children up to 3 years of age who were cleared of parasites and monitored for 8 months was 163/100 person-years under UPS and 63 under ITPS (adjusted odds ratio [AOR] = 0.40, 95% confidence interval [CI] = 0.33-0.47). In Tobanda incidence was 157/100 person-years under UPS and 134 under ITPS (AOR = 0.85, 95% CI = 0.75-0.95). Protective efficacy was 61% under fully lined ITPS and 15% under roof lined ITPS. Anemia rates improved under ITPS in both camps. This novel tool proved to be a convenient, safe, and long-lasting method of malaria control when used as a full shelter lining in an emergency setting. Copyright © 2012 by The American Society of Tropical Medicine and Hygiene.

Author Keywords

[No Keywords available]

Index Keywords

insecticide treated plastic sheeting untreated polyethylene sheeting Kaplan-Meier Estimate refugee Prospective Studies human Refugees Cohort Studies Polyethylene malaria control Animals Sierra Leone epidemiological data school child patient safety anemia Humans Adolescent insecticide male preschool child female Infant Child, Preschool Double-Blind Method observational study prevalence Incidence Disease Outbreaks Article disease transmission major clinical study Malaria, Falciparum malaria falciparum Plasmodium falciparum Insecticides cohort analysis emergency shelter Nitriles bed net Pyrethrins clinical effectiveness Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84864880189&doi=10.4269%2fajtmh.2012.11-0744&partnerID=40&md5=11995db7f7661435fb5664014cbd22df
DOI: 10.4269/ajtmh.2012.11-0744
ISSN: 00029637
Cited by: 18
Original Language: English