PLoS ONE
Volume 7, Issue 4, 2012

Sex differences in risk factors for cardiovascular disease: The PERU MIGRANT study (Article) (Open Access)

Bernabe-Ortiz A. , Benziger C.P. , Gilman R.H. , Smeeth L. , Miranda J.J.
  • a CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru, Epidemiology Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru
  • b CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru, University of Minnesota Medical School, Minneapolis, MN, United States
  • c CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States, Área de Investigación y Desarrollo, A.B. PRISMA, Lima, Peru
  • d CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
  • e CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom, Department of Medicine, School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru

Abstract

Introduction: Although men and women have similar risk factors for cardiovascular disease, many social behaviors in developing countries differ by sex. Rural-to-urban migrants have different cardiovascular risk profiles than rural or urban dwellers. The objective of this study was to evaluate the sex differences with specific cardiovascular risk factors in rural-tourban migrants. Methods and Results: We used the rural-to-urban migrant group of the PERU MIGRANT cross-sectional study to investigate the sex differences in specific cardiovascular risk factors: obesity, hypertension, metabolic syndrome, as well as exposures of socioeconomic status, acculturation surrogates and behavioral characteristics. Logistic regression analysis was used to characterize strength of association between sex and our outcomes adjusting for potential confounders. The sample of migrants was 589 (mean age 46.5 years) and 52.4% were female. In the adjusted models, women were more likely to be obese (OR=5.97; 95%CI: 3.21-11) and have metabolic syndrome (OR=2.22; 95%CI: 1.39-3.55) than men, explaining the greatest variability for obesity and metabolic syndrome but not for hypertension. Conclusions: Our results suggest that interventions for CVD in Peru should be sex-specific and address the unique health needs of migrant populations living in urban shantytowns since the risk factors for obesity and metabolic syndrome differ between males and females. © 2012 Bernabe-Ortiz et al.

Author Keywords

[No Keywords available]

Index Keywords

residential mobility urban population cardiovascular risk metabolic syndrome X logistic regression analysis Cardiovascular Diseases human sex difference risk assessment middle aged statistics rural population controlled study obesity hyperventilation hypertension PERU MIGRANT study Cross-Sectional Studies social status cross-sectional study Humans cardiovascular disease male Acculturation female risk factor Risk Factors cultural factor Article adult migration Sex Factors antihypertensive agent outcome assessment social class Peru population migration health care need types of study
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84859359058&doi=10.1371%2fjournal.pone.0035127&partnerID=40&md5=957968ac493df5205281ed2400aaa10f
DOI: 10.1371/journal.pone.0035127
ISSN: 19326203
Cited by: 19
Original Language: English