Osteopathic Family Physician
Volume 4, Issue 2, 2012, Pages 60-62

Exostosis and seizures in an adolescent refugee patient-case study of pseudohypoparathyroidism (Article)

Olsen R.Q.* , Edwards E.S. , Brackenrich W.L.
  • a Virginia Tech-Carilion School of Medicine Family Medicine Residency Program, Roanoke, VA, United States
  • b Virginia Tech-Carilion School of Medicine Family Medicine Residency Program, Roanoke, VA, United States
  • c Virginia Tech-Carilion School of Medicine Family Medicine Residency Program, Roanoke, VA, United States

Abstract

Pseudohypoparathyroidism is a complex endocrine disorder caused by various possible biochemical receptor abnormalities of the parathyroid hormone. Phenotypical features that result depend heavily on the type of pseudohypoparathyroidism and genetic inheritance (maternal versus paternal inheritance). We discuss a case of an 18-year-old female refugee who presented as a new patient with multiple complaints including seizure disorder fitting the phenotypical syndrome known as Albright's hereditary osteodystrophy. Allopathic treatment and theoretical osteopathic therapies that can be used are discussed. © 2012 Elsevier Inc.

Author Keywords

Exostosis Pseudohypoparathyroidism Albright's hereditary osteodystrophy GNAS gene

Index Keywords

visual impairment refugee steroid dermatitis phosphorus human phenotype steroid therapy priority journal thyrotropin Calcium foot pain phosphate blood level parathyroid hormone calcium blood level case report female Article adult drug eruption Albright syndrome phenobarbital thyrotropin blood level pseudohypoparathyroidism cataract exostosis seizure parathyroid hormone blood level
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857446223&doi=10.1016%2fj.osfp.2010.06.001&partnerID=40&md5=85e0036714026582984f5b122abe19c6
DOI: 10.1016/j.osfp.2010.06.001
ISSN: 1877573X
Original Language: English