Revue des Maladies Respiratoires
Volume 29, Issue 7, 2012, Pages 858-870

Comparative epidemiological study of the tuberculosis-migrant and native subjects in Guadeloupe from 2006 to 2011 [Etude epidemiologique comparative de la tuberculose des sujets migrants et natifs en Guadeloupe de 2006 a 2011] (Article)

Cadelis G.* , Rossigneux E. , Millet J. , Rastogi N.
  • a Service de Pneumologie, CHU de Pointe-a-Pitre, route de Chauvel, Pointe-a-Pitre Cedex, 97159, Guadeloupe, Centre de Lutte Antituberculeux de la Guadeloupe, CHU de Pointe-a-Pitre, Pointe-a-Pitre Cedex, 97159, Guadeloupe
  • b Service de Pneumologie, CHU de Pointe-a-Pitre, route de Chauvel, Pointe-a-Pitre Cedex, 97159, Guadeloupe
  • c Unite de la Tuberculose et des Mycobacteries, Laboratoire Supranational de l'Oms Pour la Tuberculose, Institut Pasteur de la Guadeloupe, Pointe-a-Pitre Cedex, 97159, Guadeloupe
  • d Unite de la Tuberculose et des Mycobacteries, Laboratoire Supranational de l'Oms Pour la Tuberculose, Institut Pasteur de la Guadeloupe, Pointe-a-Pitre Cedex, 97159, Guadeloupe

Abstract

Most of the migrants residing in Guadeloupe are from neighboring Caribbean islands, some of which are characterized by a high incidence of tuberculosis. The objective of this retrospective and observational study was to define the epidemiological characteristics of tuberculosis affecting migrant and native populations in Guadeloupe. Methods.-We describe all cases of tuberculosis in Guadeloupe identified in these two populations between 1 July 2006 and 30 June 2011. Results.-The incidence of TB among migrants in Guadeloupe was seven times higher than that in native subjects in 2010 (33.4 vs. 5.5 new cases/100,000 inhabitants). Tuberculosis affecting the migrant population was characterized by young age of the patients (42 vs. 55 years) and a significant proportion of co-infection by the human immunodeficiency virus (HIV) (47 vs. 14%, P > 0.001). Among the patient population studied, the HIV infection increased the risk of developing severe tuberculosis (adjusted odds ratio: 2.9; 95%CI: 1.2-6.8). Moreover, HIV infection was also a risk factor for death where the infection was not controlled (CD4 count > 200 units per microliter; adj risk ratio: 3.9; 1.2-12.4). Conclusion.-This study shows that the migrant population in Guadeloupe is at increased risk of tuberculosis and should be considered as a priority target for tuberculosis control program. © 2012 SPLF.

Author Keywords

Guadeloupe tuberculosis Epidemiology immigrants

Index Keywords

HIV Infections Human immunodeficiency virus infection human middle aged statistics AIDS-Related Opportunistic Infections comparative study Humans migrant male CD4 lymphocyte count female tuberculosis risk factor Risk Factors observational study Guadeloupe Coinfection Incidence Article Retrospective Studies AIDS related complex major clinical study adult migration Transients and Migrants retrospective study mortality mixed infection
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84874404318&doi=10.1016%2fj.rmr.2012.05.003&partnerID=40&md5=e5994519afe5dd0b852510cf6fa1b708
DOI: 10.1016/j.rmr.2012.05.003
ISSN: 07618425
Cited by: 7
Original Language: French