Anales de Pediatria
Volume 74, Issue 6, 2011, Pages 409-412

Vitamin D intoxication in infants born from Latin-American immigrants. Series of 3 cases [Intoxicación por vitamina D en hijos de inmigrantes latinoamericanos. Serie de 3 casos] (Article) (Open Access)

Alonso Canal L. , Ruiz Herrero J.* , Villalobos Reales J. , Gaitero Tristán J. , Pérez Rodríguez T. , Cañedo Villaroya E.
  • a Hospital Infantil Universitario Niño Jesús, Madrid, Spain
  • b Hospital Infantil Universitario Niño Jesús, Madrid, Spain
  • c Hospital Infantil Universitario Niño Jesús, Madrid, Spain
  • d Hospital Infantil Universitario Niño Jesús, Madrid, Spain
  • e Hospital Infantil Universitario Niño Jesús, Madrid, Spain
  • f Hospital Infantil Universitario Niño Jesús, Madrid, Spain

Abstract

Vitamin D intoxication is a well-known cause of hypercalcemia in children and can have serious consequences (renal, cardiac and neurologic mainly). The use of the so-called over-the-counter (OTC) supplements involves a high risk in this taking place. The clinical expression of hypercalcaemia is unspecific, and, together with the fact that the administration of such supplements is frequently denied, the diagnosis of vitamin D intoxication is often delayed and the number of complementary tests performed is high. We here-for expose a series of 3 cases all of which are infants born from Latin-American immigrants who were receiving supplements that came from their parents originary countries. All 3 cases were admitted in our hospital within a period of 5 months. After the first preceding case, the diagnosis of the 2 latter ones was performed promptly and so was the instauration of the treatment for hypercalcemia. The initial levels of serum calcium and of 25-hydroxy vitamin D where, respectively for each case: 17.9 mg/dl and 504 ng/ml; 14.46 mg/dl and 505 ng/ml; 14.2 mg/dl and 530 ng/ml. All 3 patients received intravenous treatment with serum, furosemide and corticoids and in one case with subcutaneous calcitonine as well. The clinical outcome was optimal for them all, with normalization of the calcium levels and of the renal function. © 2010 Asociación Española de Pediatría. Published by Elsevier España, S.L. All rights reserved.

Author Keywords

Dietary supplementation Over-the-counter drugs Hypercalcemia Vitamin D intoxication

Index Keywords

infant disease Emigrants and Immigrants case report male Vitamin D hypercalcemia immigrant Infant Child, Preschool vitamin D intoxication Latin America Article human Humans Hispanic
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-79957907511&doi=10.1016%2fj.anpedi.2011.01.018&partnerID=40&md5=f6f454a95a63b1e44baab82ebfb77b1b
DOI: 10.1016/j.anpedi.2011.01.018
ISSN: 16954033
Cited by: 2
Original Language: Spanish