Osteoporosis International
Volume 22, Issue 5, 2011, Pages 1343-1353

Socioeconomic status and bone health in community-dwelling older men: The CHAMP Study (Article)

Nabipour I. , Cumming R. , Handelsman D.J. , Litchfield M. , Naganathan V. , Waite L. , Creasey H. , Janu M. , Le Couteur D. , Sambrook P.N. , Seibel M.J.
  • a Bone Research Program, ANZAC Research Institute, University of Sydney, Concord, NSW 2139, Australia, Department of Endocrine and Metabolic Diseases, Persian Gulf Tropical Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, Iran
  • b School of Public Health, University of Sydney, Sydney, NSW, Australia
  • c Department of Andrology, ANZAC Research Institute, University of Sydney, Sydney, NSW, Australia
  • d Centre for Education and Research on Ageing, Concord Hospital, University of Sydney, Sydney, NSW, Australia
  • e Centre for Education and Research on Ageing, Concord Hospital, University of Sydney, Sydney, NSW, Australia
  • f Centre for Education and Research on Ageing, Concord Hospital, University of Sydney, Sydney, NSW, Australia
  • g Centre for Education and Research on Ageing, Concord Hospital, University of Sydney, Sydney, NSW, Australia
  • h Sydney South West Pathology Service, Concord Hospital, Sydney, NSW, Australia
  • i Centre for Education and Research on Ageing, Concord Hospital, University of Sydney, Sydney, NSW, Australia
  • j Institute of Bone and Joint Research, Royal North Shore Hospital, University of Sydney, Sydney, NSW, Australia
  • k Bone Research Program, ANZAC Research Institute, University of Sydney, Concord, NSW 2139, Australia

Abstract

The association between socioeconomic status (SES) and bone health, specifically in men, is unclear. Based upon data from the large prospective Concord Health in Ageing Men Project (CHAMP) Study of community-dwelling men aged 70 years or over, we found that specific sub-characteristics of SES, namely, marital status, living circumstances, and acculturation, reflected bone health in older Australian men. Introduction: Previous studies reported conflicting results regarding the relationship between SES and bone health, specifically in men. The main objective of this study was to investigate associations of SES with bone health in community-dwelling men aged 70 years or over who participated in the baseline phase of the CHAMP Study in Sydney, Australia. Methods: The Australian Socioeconomic Index 2006 (AUSEI06) based on the Australian and New Zealand Standard Classification of Occupations was used to determine SES in 1,705 men. Bone mineral density and bone mineral content (BMC) were determined by dual-energy X-ray absorptiometry. Bone-related biochemical and hormonal parameters, including markers of bone turnover, parathyroid hormone, and vitamin D, were measured in all men. Results: General linear models adjusted for age, weight, height, and bone area revealed no significant differences across crude AUSEI06 score quintiles for BMC at any skeletal site or for any of the bone-related biochemical measures. However, multivariate regression models revealed that in Australian-born men, marital status was a predictor of higher lumbar BMC (β=0.07, =0.002), higher total body BMC (β=0.05, =0.03), and lower urinary NTX-I levels (β=-0.08, =0.03), while living alone was associated with lower BMC at the lumbar spine (β=-0.05, =0.04) and higher urinary NTX-I levels (β=0.07, =0.04). Marital status was also a predictor of higher total body BMC (β=0.14, =0.003) in immigrants from Eastern and South Eastern Europe. However, in immigrants from Southern Europe, living alone and acculturation were predictors of higher femoral neck BMC (β=0.11, =0.03) and lumbar spine BMC (β=0.10, =0.008), respectively. Conclusions: Although crude occupation-based SES scores were not significantly associated with bone health in older Australian men, specific sub-characteristics of SES, namely, marital status, living circumstances, and acculturation, were predictors of bone health in both Australia-born men and European immigrants. © 2010 International Osteoporosis Foundation and National Osteoporosis Foundation.

Author Keywords

Socioeconomic status Bone health Bone turnover Complex systems Bone mineral density Immigration

Index Keywords

dual energy X ray absorptiometry protein urine level vertebra malformation aminoterminal propeptide of type 1 collagen Collagen immigrant Absorptiometry, Photon Hip Joint bone turnover pension bisphosphonic acid derivative bone health Australia alcohol consumption phosphorus vitamin blood level calcifediol Prospective Studies human corticosteroid therapy Vitamin D priority journal health status Marital Status Aged Calcium alkaline phosphatase blood level academic achievement marriage alkaline phosphatase social status parathyroid hormone Humans smoking calcium blood level male osteoporosis Aged, 80 and over prediction unclassified drug cultural factor New South Wales Article Femur Neck Bone Density age diet supplementation body weight protein blood level bone mineral correlational study normal human Emigration and Immigration anthropometry lumbar spine testosterone Lumbar Vertebrae body mass body height social class parathyroid hormone blood level
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-79955476580&doi=10.1007%2fs00198-010-1332-0&partnerID=40&md5=81581ec357e4b6689dfbc1371b5782dc
DOI: 10.1007/s00198-010-1332-0
ISSN: 0937941X
Cited by: 13
Original Language: English