European Journal of Cancer
Volume 46, Issue 3, 2010, Pages 599-605

Cancer incidence among Iranian immigrants in Sweden and Iranian residents compared to the native Swedish population (Article)

Mousavi S.M.* , Brandt A. , Weires M. , Ji J. , Sundquist J. , Hemminki K.
  • a Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany
  • b Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany
  • c Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany
  • d Center for Primary Care Research, Lund University, Malmö, Sweden
  • e Center for Primary Care Research, Lund University, Malmö, Sweden, Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA, United States
  • f Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany, Center for Primary Care Research, Lund University, Malmö, Sweden, Center for Family and Community Medicine, Karolinska Institute, 14183 Huddinge, Sweden

Abstract

Background and goals: Comparing cancer incidence by migrant studies is one of the main approaches to generate hypotheses on the aetiology of cancer. Immigrant studies are most informative when cancer incidence data are available from both the source and the host country. Methods: The age standardised incidence rate (ASR) and standardised incidence ratio (SIR) of cancers among the Iranian immigrants were compared to the native Swedish population as the standard population by using the Swedish Family-Cancer Database (FCD) from 1958 to 2006. We also compared SIRs between Iranian immigrants and Iranian residents for whom the data were derived from the Iranian national cancer registry report of 2006. Results: Among the 65,501 Iranian immigrants, the median age at immigration was 26 years and the median length of stay was 16 years. Their all-cancer ASR was 175.3 and 153.1 per 100,000 person years for males and females, respectively, during the period from 1996 to 2006, higher than for the Iranian residents. The ASRs increased among the male Iranian immigrants during the past two decades but were stable among females. The risk for all-cancers among Iranian immigrants was lower than that for the native Swedish population. The Iranian immigrants had a significantly increased risk for male urinary bladder (SIR = 1.40) and thyroid cancers (2.64) compared to the Swedes. Conclusion: The reasons for the decreased risk for all-cancers among the Iranian immigrants remain to be established. The ASR difference between the Iranian immigrants and the Iranian residents may be due to the differences between the registry systems, selected immigrant groups and environmental exposures. © 2009 Elsevier Ltd. All rights reserved.

Author Keywords

Incidence Immigration cancer Risk

Index Keywords

immigrant Neoplasms human immigration middle aged data base priority journal Aged cancer risk cancer epidemiology Iran Young Adult Sweden Humans Urinary Bladder Neoplasms Adolescent Infant, Newborn male female Aged, 80 and over Infant Thyroid Neoplasms Child, Preschool environmental exposure thyroid cancer cancer registry bladder cancer Incidence Article major clinical study adult Transients and Migrants cancer localization standardized incidence ratio cancer incidence Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-75149176676&doi=10.1016%2fj.ejca.2009.10.009&partnerID=40&md5=29a7cc4414ecea83a939fa43cd912285
DOI: 10.1016/j.ejca.2009.10.009
ISSN: 09598049
Cited by: 13
Original Language: English