The Lancet
Volume 318, Issue 8257, 1981, Pages 1199-1201

ANNUAL HIGH-DOSE VITAMIN D PROPHYLAXIS IN ASIAN IMMIGRANTS (Article)

Stephens W.P.* , Berry J.L. , Klimiuk P.S. , Mawer E.B.
  • a Department of Medicine, Manchester Royal Infirmary, Manchester, M13 9PL, United Kingdom
  • b Department of Medicine, Manchester Royal Infirmary, Manchester, M13 9PL, United Kingdom
  • c Department of Medicine, Manchester Royal Infirmary, Manchester, M13 9PL, United Kingdom
  • d Department of Medicine, Manchester Royal Infirmary, Manchester, M13 9PL, United Kingdom

Abstract

A group of vitamin-D-depleted Asians was identified in the spring of 1980 and treated with 2.5 mg ergocalciferol in the autumn of that year. Treatment produced a sustained rise in the serum level of 25-hydroxyvitamin D which lasted until the spring of 1981. The response was more predictable after oral than after intramuscular administration. Treatment in the autumn provides an effective, efficient, and cheap means of prophylaxis against vitamin D deficiency in Asians during the winter. A "once a year" regimen promises a much higher compliance rate than could be achieved by daily supplementation. © 1981.

Author Keywords

[No Keywords available]

Index Keywords

ergocalciferol immigrant Hydroxycholecalciferols human epidemiology Asia Administration, Oral Seasons Great Britain season Adolescent male case report female vitamin D deficiency prevention prophylaxis adult Support, Non-U.S. Gov't major clinical study United Kingdom ethnic or racial aspects Emigration and Immigration Injections, Intramuscular Middle Age Ergocalciferols
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019867441&doi=10.1016%2fS0140-6736%2881%2991439-2&partnerID=40&md5=f350208c4baeb7ebe219ca5c406583b4
DOI: 10.1016/S0140-6736(81)91439-2
ISSN: 01406736
Cited by: 38
Original Language: English