Diabetes Research and Clinical Practice
Volume 130, 2017, Pages 196-203

Comparison of type 2 diabetes prevalence in Chinese migrants vs Caucasians and new perspectives for screening of cerebrovascular disease in Chinese: A proof of concept study (Article)

Modesti P.A.* , Castellani S. , Calabrese M. , Malandrino D. , Zhao D.
  • a Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, Florence, 50134, Italy
  • b Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, Florence, 50134, Italy
  • c Diabetology Unit, Ospedale Misericordia e Dolce, Prato, Italy
  • d Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, Florence, 50134, Italy
  • e Department of Epidemiology, Capital Medical University Affiliated Beijing Anzhen Hospital, Beijing Institute of Heart, Lung & Blood Vessel Diseases, Anzhenli, Chaoyang District, Beijing, 100029, China

Abstract

Aims Type 2 diabetes (T2DM) is a recognized risk factor for intracranial stenosis (ICS) in China where ischemic stroke is a health priority. In Europe little information is available on T2DM prevalence among Chinese minority groups and vascular screening is commonly limited to extracranial vessels. Feasibility of community-based T2DM screening, differences in T2DM prevalence between Chinese migrants and Italians, and prevalence of ICS among Chinese patients with newly diagnosed T2DM were investigated. Methods Chinese first generation migrants (n = 1200) and native Italians (n = 291) aged 35–59 years were enrolled in a cross-sectional survey. Diagnosis of T2DM was based on fasting plasma glucose and/or current treatment with glucose-lowering drugs. Newly diagnosed Chinese patients were screened for ICS using Doppler ultrasound. Results T2DM was more prevalent among Chinese (n = 168, 14.0%) than Italians (n = 21, 7.3%) (age- and gender adjusted OR 2.29; 95% C.L. 1.41–3.72). Prevalence of ICS among newly diagnosed Chinese was 18.2%. Nine out of the 17 patients with any ICS (52%) had >1 intracranial lesion. Conclusions T2DM screening within the Chinese community was feasible revealing prevalence twice as much as in the Italian cohort; the 18% prevalence of ICS in newly diagnosed Chinese patients stresses the need of implementing appropriate vascular screening strategies. © 2017 Elsevier B.V.

Author Keywords

Transcranial Doppler ultrasound Plaque, atherosclerotic Intracranial atherosclerosis stenosis minority groups Diabetes mellitus Prevalence

Index Keywords

China Chinese Caucasian race difference non insulin dependent diabetes mellitus minority group Diabetes Mellitus, Type 2 human Asian continental ancestry group statistics and numerical data comparative study ethnology Cross-Sectional Studies cross-sectional study migrant Humans male Italian (citizen) female risk factor Risk Factors prevalence Article major clinical study adult migration European Continental Ancestry Group Italy Doppler flowmetry proof of concept Transients and Migrants intracranial stenosis Proof of Concept Study cerebrovascular disease
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021105104&doi=10.1016%2fj.diabres.2017.05.023&partnerID=40&md5=0f030d0615fa3362cc7de54147381dfe
DOI: 10.1016/j.diabres.2017.05.023
ISSN: 01688227
Cited by: 8
Original Language: English