Human Vaccines and Immunotherapeutics
2019

Estimating population immunity to poliovirus in Jordan’s high-risk areas (Article)

Farag N.H.* , Wannemuehler K. , Weldon W. , Arbaji A. , Belbaisi A. , Khuri-Bulos N. , Ehrhardt D. , Surour M.R. , ElhajQasem N.S. , Al-Abdallat M.M.
  • a Global Immunizations Division, Centers for Disease Control and Prevention, Atlanta, GA, United States
  • b Global Immunizations Division, Centers for Disease Control and Prevention, Atlanta, GA, United States
  • c National Center for Infectious Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States
  • d Eastern Mediterranean Public Health Network (EMPHNET), Amman, Jordan
  • e Department of Pediatrics, University of Jordan, Amman, Jordan
  • f Department of Pediatrics, University of Jordan, Amman, Jordan
  • g Global Immunizations Division, Centers for Disease Control and Prevention, Atlanta, GA, United States
  • h Communicable Disease Directorate, Ministry of Health, Amman, Jordan
  • i Communicable Disease Directorate, Ministry of Health, Amman, Jordan
  • j Communicable Disease Directorate, Ministry of Health, Amman, Jordan

Abstract

A community-based serosurvey was conducted among children ages 6–59 to assess population immunity in Jordan’s high-risk areas following the Middle East polio outbreak response. The survey was a two-stage cluster-quota sample with high risk areas as the primary sampling units. High-risk areas included border and hard-to-reach areas, and areas with a high proportion of refugees, mobile communities and/or low coverage during previous immunization campaigns. Population immunity to poliovirus was high overall. In high-risk areas, Type 1 seroprevalence = 98% (95% CI = 96, 99), Type 2 = 98% (95% CI = 96, 99) and Type 3 = 96% (95% CI = 94, 98). Seroprevalence was higher in the refugee camps: Type 1 seroprevalence = 99.6% (95% CI = 97.9, 100); Type 2: 99.6% (95% CI = 97.9, 99.9), and Type 3: 100% (95% CI = 100,100). The vigilance that the Jordan Ministry of Health has placed on locating and vaccinating high-risk populations has been successful in maintaining high population immunity and averting polio outbreaks despite the influx of refugees from Syria. ©, This work was authored as part of the Contributor’s official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 U.S.C. 105, no copyright protection is available for such works under U.S. Law.

Author Keywords

Seroprevalence Poliovirus immunization strategy oral polio vaccine Jordan

Index Keywords

[No Keywords available]
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85075072468&doi=10.1080%2f21645515.2019.1667727&partnerID=40&md5=f18a2e94077f19bd834df92eaefa9486
DOI: 10.1080/21645515.2019.1667727
ISSN: 21645515
Original Language: English