Public Health Nutrition
2019

Skinfold thickness and the incidence of type 2 diabetes mellitus and hypertension: An analysis of the PERU MIGRANT study (Article)

Ruiz-Alejos A. , Carrillo-Larco R.M. , Miranda J.J. , Gilman R.H. , Smeeth L. , Bernabé-Ortiz A.*
  • a CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Armendariz 445, Miraflores, Lima, Peru
  • b CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Armendariz 445, Miraflores, Lima, Peru
  • c CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Armendariz 445, Miraflores, Lima, Peru, Department of Medicine, School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru
  • d CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Armendariz 445, Miraflores, Lima, Peru, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States
  • e Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
  • f CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Armendariz 445, Miraflores, Lima, Peru, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom

Abstract

Objective:To determine the association between excess body fat, assessed by skinfold thickness, and the incidence of type 2 diabetes mellitus (T2DM) and hypertension (HT).Design:Data from the ongoing PERU MIGRANT Study were analysed. The outcomes were T2DM and HT, and the exposure was skinfold thickness measured in bicipital, tricipital, subscapular and suprailiac areas. The Durnin-Womersley formula and SIRI equation were used for body fat percentage estimation. Risk ratios and population attributable fractions (PAF) were calculated using Poisson regression.Setting:Rural (Ayacucho) and urban shantytown district (San Juan de Miraflores, Lima) in Peru.Participants:Adults (n 988) aged ≥30 years (rural, rural-to-urban migrants, urban) completed the baseline study. A total of 785 and 690 were included in T2DM and HT incidence analysis, respectively.Results:At baseline, age mean was 48·0 (sd 12·0) years and 47 % were males. For T2DM, in 7·6 (sd 1·3) years, sixty-one new cases were identified, overall incidence of 1·0 (95 % CI 0·8, 1·3) per 100 person-years. Bicipital and subscapular skinfolds were associated with 2·8-fold and 6·4-fold risk of developing T2DM. On the other hand, in 6·5 (sd 2·5) years, overall incidence of HT was 2·6 (95 % CI 2·2, 3·1) per 100 person-years. Subscapular and overall fat obesity were associated with 2·4- and 2·9-fold risk for developing HT. The PAF for subscapular skinfold was 73·6 and 39·2 % for T2DM and HT, respectively.Conclusions:We found a strong association between subscapular skinfold thickness and developing T2DM and HT. Skinfold assessment can be a laboratory-free strategy to identify high-risk HT and T2DM cases. © The Authors 2019.

Author Keywords

Hypertension Skinfold thickness Obesity Type 2 diabetes mellitus

Index Keywords

[No Keywords available]
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066852426&doi=10.1017%2fS1368980019001307&partnerID=40&md5=7f4e0dbf291775c75c490dd697eeff84
DOI: 10.1017/S1368980019001307
ISSN: 13689800
Original Language: English