Aim. To study heart rate variability (HRV) in patients with biliary problems and hypertension depending on duration of their life in the North. Material and methods. A standardized screening of 1014 workers living in Mirny (Yakutia) according to the WHO/CINDI Euro regional committee program was performed. Conclusion. With an increase of duration of living in the North patients with biliary diseases combined with arterial hypertension develop disorders of humoral-metabolic regulation mechanisms, increased parasympathetic activity, imbalance of the autonomic nervous system.

Duration of residence Biliary diseases arterial hypertension Heart rate variability North

autonomic nervous system heart adaptation Heart Rate physiology human Arctic hypertension Time Factors Biliary Tract Diseases innervation Young Adult Humans Adolescent male preschool child biliary tract disease Infant Child, Preschool female Article Adaptation, Physiological adult Arctic Regions pathophysiology time Child