American Journal of Tropical Medicine and Hygiene
Volume 80, Issue 3, 2009, Pages 425-430

Community based parasitic screening and treatment of sudanese refugees: Application and assessment of centers for disease control guidelines (Article)

Brodine S.K. , Thomas A. , Huang R. , Harbertson J. , Mehta S. , Leake J. , Nutman T. , Moser K. , Wolf J. , Ramanathan R. , Burbelo P. , Nou J. , Wilkins P. , Reed S.L.
  • a Graduate School of Public Health, MC 4162, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, United States
  • b Graduate School of Public Health, MC 4162, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, United States
  • c UCSD Medical Center, 200 W. Arbor Dr, San Diego, CA 92103-8416, United States
  • d Graduate School of Public Health, MC 4162, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, United States
  • e UCSD Medical Center, 200 W. Arbor Dr, San Diego, CA 92103-8416, United States
  • f Division of Infectious Diseases, Rady Children's Hospital, MC5041, 3020 Children's Way, San Diego, CA 92123, United States
  • g Laboratory of Parasitic Diseases, Bldg 4, National Institutes of Health, Center Dr, Bethesda, MD 20892-0425, United States
  • h TB Control and Refugee Health Services Branch, County of San Diego Health and Human Services Agency, MS P576, 3851 Rosecrans St, San Diego, CA 92110, United States
  • i Graduate School of Public Health, MC 4162, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, United States
  • j TB Control and Refugee Health Services Branch, County of San Diego Health and Human Services Agency, MS P576, 3851 Rosecrans St, San Diego, CA 92110, United States
  • k Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, United States
  • l Reference Diagnostic Laboratory, Division of Parasitic Diseases, Centers for Disease Control, Atlanta, GA 30341, United States
  • m Reference Diagnostic Laboratory, Division of Parasitic Diseases, Centers for Disease Control, Atlanta, GA 30341, United States
  • n Graduate School of Public Health, MC 4162, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, United States, UCSD Medical Center, 200 W. Arbor Dr, San Diego, CA 92103-8416, United States

Abstract

Centers for Disease Control guidelines for schistosomiasis and strongyloidiasis in Sudanese and Somali refugees are not widely implemented. Given limited prevalence data, we conducted a seroprevalence study of schistosomiasis, strongyloidiasis, and loiasis in Sudanese refugees across diverse ages. Sudanese refugees, ages 4-78, were recruited via community organizations. Half of the patients (86/172), were seropositive for schistosomiasis (46/171; 26.9%), strongyloidiasis (56/172; 33%), or both (16/171; 9.4%). No Loa loa infections were detected. Infection rates were similar in adults and children except that no schistosomiasis was detected in children < 4 years of age at the time of immigration to the United States. The high prevalence of schistosomiasis and strongyloidiasis in a community-based sample of Sudanese confirms the urgency for compliance with CDC refugee health guidelines. We detected no co-infection with Loa loa using the most sensitive serologic techniques, allowing use of ivermectin, the most effective treatment of strongyloidiasis. Copyright © 2009 by The American Society of Tropical Medicine and Hygiene.

Author Keywords

[No Keywords available]

Index Keywords

Strongyloidiasis refugee Anthelmintics parasite identification dose response human immigration Refugees middle aged Sudan Practice Guidelines as Topic Aged ivermectin drug efficacy Cross-Sectional Studies laboratory test Young Adult United States school child Centers for Disease Control and Prevention (U.S.) Humans Adolescent mebendazole male preschool child Albendazole loiasis parasite examination Child, Preschool female Article disease control major clinical study adult schistosomiasis serology drug tolerability helminthiasis praziquantel Loa loa seroprevalence Seroepidemiologic Studies Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-62949172257&partnerID=40&md5=bb5abee7ec27d15f7306a441d88e1644
ISSN: 00029637
Cited by: 15
Original Language: English