Megaloblastic anaemia due to vitamin B12 deficiency is rare in childhood. However, as most cases are due to maternal insufficiency, it is mainly seen in breastfed infants especially when the mother's socioeconomic status is low and the nutrition is not adequate. We present case of two Syrian refugee infants with severe vitamin B12 deficiency with pancytopenia, hepatosplenomegaly and leukoerythroblastosis. Copyright 2014 BMJ Publishing Group. All rights reserved.

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treatment response disease classification differential diagnosis Diagnosis, Differential refugee iron deficiency anemia hemoglobin blood level Syrian Arab Republic complication clinical feature hepatosplenomegaly human hepatomegaly Refugees recurrent infection reticulocyte count cyanocobalamin splenomegaly bone marrow examination Precursor Cell Lymphoblastic Leukemia-Lymphoma failure to thrive priority journal Anemia, Myelophthisic muscle hypotonia Pancytopenia blood smear mean corpuscular volume megakaryocyte Anemia, Pernicious reflex disorder thrombocyte count acute leukemia lactate dehydrogenase blood level lactate dehydrogenase tendon reflex myelophthisic anemia erythrocyte count human cell Humans male case report Infant neutrophil count leukocyte count Article petechia cyanocobalamin deficiency Syria Turkey irritability pallor hematocrit hemoglobin disease severity Child