Journal of Medical Microbiology
Volume 57, Issue 11, 2008, Pages 1420-1423

Brain and lung metastasis of alveolar echinococcosis in a refugee from a hyperendemic area (Article) (Open Access)

Tappe D.* , Weise D. , Ziegler U. , Müller A. , Müllges W. , Stich A.
  • a German Consiliary Laboratory for Echinococcosis, Institute of Hygiene and Microbiology, University of Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany, Department of Tropical Medicine, Medical Mission Hospital, Salvatorstrasse 7, 97067 Würzburg, Germany
  • b Department of Neurology, University Hospital of Würzburg, Josef-Scheider-Strasse 11, 97080 Würzburg, Germany
  • c Department of Tropical Medicine, Medical Mission Hospital, Salvatorstrasse 7, 97067 Würzburg, Germany
  • d Department of Tropical Medicine, Medical Mission Hospital, Salvatorstrasse 7, 97067 Würzburg, Germany
  • e Department of Neurology, University Hospital of Würzburg, Josef-Scheider-Strasse 11, 97080 Würzburg, Germany
  • f Department of Tropical Medicine, Medical Mission Hospital, Salvatorstrasse 7, 97067 Würzburg, Germany

Abstract

Alveolar echinococcosis (AE) of the liver with cerebral and pulmonary metastasis was diagnosed in a Tibetan monk who initially presented with severe headache to an emergency department in Germany. Multiple lesions with perifocal oedema and severe compression of the third ventricle were seen with computed tomography (CT) of the brain. Glioma or cerebral metastasis of a hitherto undiagnosed abdominal or pulmonary malignancy was suspected. CT scans of the lung and liver demonstrated further tumorous masses. Magnetic resonance imaging of the brain revealed the cystic nature of the cerebral lesions and the patient had a highly positive serology for AE. The echinococcal aetiology of the brain lesions was confirmed by PCR for this refugee from an area where two disease entities, AE and cystic echinococcosis, are hyperendemic. © 2008 SGM.

Author Keywords

[No Keywords available]

Index Keywords

lung lesion liver tumor Germany differential diagnosis refugee lung cancer low drug dose follow up human Refugees gadolinium middle aged Echinococcosis, Pulmonary brain cerebrospinal fluid analysis cross reaction priority journal nausea emergency ward tendon reflex nucleotide sequence Humans Treatment Outcome headache Lung male case report lung tumor Albendazole brain tomography fluorodeoxyglucose f 18 enzyme linked immunosorbent assay liver hydatid cyst nuclear magnetic resonance imaging serodiagnosis antibody screening polymerase chain reaction neuroimaging Article amplicon positron emission tomography brain damage abdominal cancer adult brain edema brain metastasis serology glioma mannitol brain third ventricle endemic disease central nervous system tuberculosis agar gel electrophoresis computer assisted tomography lung metastasis dexamethasone seizure Physical Examination immunoassay Western blotting

Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-55549110785&doi=10.1099%2fjmm.0.2008%2f002816-0&partnerID=40&md5=e55e74798cd411f5d8cab8ee9927dddb

DOI: 10.1099/jmm.0.2008/002816-0
ISSN: 00222615
Cited by: 23
Original Language: English