Journal of Immigrant and Minority Health
Volume 10, Issue 5, 2008, Pages 469-474

Sero-epidemiology of hepatitis B among new refugees to Minnesota (Article)

Ugwu C. , Varkey P.* , Bagniewski S. , Lesnick T.
  • a Department of Medicine, Buffalo Clinic, University of Minnesota, Buffalo, MN, United States
  • b Division of Preventive Medicine, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, MN 55905, United States
  • c Division of Biostatistics, Mayo Clinic, Rochester, MN, United States
  • d Division of Biostatistics, Mayo Clinic, Rochester, MN, United States

Abstract

Hepatitis B virus (HBV) infection is endemic in many parts of the world, and prevailing conditions in refugee situations result in greater risk of infection. The objectives of this study were to determine the period prevalence of HBV infection among primary refugees in Minnesota during 1998-2001; describe trends in prevalence over time and identify patterns of infection and immunity in various refugee populations. A retrospective analysis of health examination data from the Minnesota Department of Health was conducted to examine serologic markers for hepatitis B: HBcAb, HbsAg, and HBsAb among 12,505 refugees who participated in the voluntary domestic health examination from 1998 to 2001. One hundred and eleven refugees had at least one immunization before arrival and were excluded. There was documented HBV test results in 8,754 (70.6%) of refugees; period prevalence of hepatitis B infection was 7.1%. Africans were three times more likely and Asians 2.4 times more likely to be infected than Europeans (P < 0.001). Older African refugees and African males were more likely to be infected than younger African refugees and women African refugees (P < 0.001). Younger persons below 30 years of age accounted for over 70% of all infected refugees in this study. Reducing the burden of infection among refugees requires enhanced provider awareness as well as intensified efforts aimed at identifying new at-risk populations, modifying risk factors, and implementing preventive and treatment strategies at various levels in the refugee resettlement process. © Springer Science+Business Media, LLC 2007.

Author Keywords

Minnesota Hepatitis B Epidemiology Refugee

Index Keywords

refugee mass screening Europe medical examination human trend study Refugees sex difference Asia middle aged risk assessment priority journal European American Logistic Models immunity Minnesota Hepatitis B virus African American United States Humans ethnic difference antibody detection Adolescent geography Infant, Newborn male Asian American female Infant Child, Preschool Risk Factors Africa prevalence Article Public Health Administration Hepatitis B Vaccines adult major clinical study awareness serology infection risk seroepidemiology endemic disease hepatitis B surface antibody hepatitis B vaccine age distribution hepatitis B surface antigen retrospective study vaccination hepatitis B Seroepidemiologic Studies risk reduction immunization Hepatitis B Antibodies hepatitis B core antibody Biological Markers Child

Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-48449091438&doi=10.1007%2fs10903-007-9111-5&partnerID=40&md5=94c220fa5663635660000d623a280711

DOI: 10.1007/s10903-007-9111-5
ISSN: 15571912
Cited by: 14
Original Language: English