Scandinavian Journal of Infectious Diseases
Volume 40, Issue 9, 2008, Pages 756-758

Helicobacter pylori and cagA seroprevalence in sub-Saharan inmigrants recently arrived to Gran Canaria (Spain) (Article)

Sanz-Peláez O. , Santana-Rodríguez E. , Angel-Moreno Maroto A. , Carranza-Rodríguez C. , Pisos-Alamo E. , Pérez-Arellano J.-L.*
  • a Sevicio de Medicina Interna, Hospital Universitario de Gran Canaria Dr. Negrin, Las Palmas de Gran Canaria, Spain
  • b Servicio de Microbiologia, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain
  • c Servicio de Medicina Interna III, Clinica Puerta de Hierro, Madrid, Spain
  • d Departamento de Ciencias Médicas y Quirurgicas, Centro de Ciencias de la Salud, Universidad de las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain
  • e Unidad de Enfermedades Infecciosas y Medicina Tropical, Servicio de Medicina Interna, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain
  • f Departamento de Ciencias Médicas y Quirurgicas, Centro de Ciencias de la Salud, Universidad de las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain, Unidad de Enfermedades Infecciosas y Medicina Tropical, Servicio de Medicina Interna, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain

Abstract

Non-ulcerous dyspepsia is common among sub-Saharan people migrating into Spain. Given the high prevalence of H. pylori (HP) infection in their countries of origin, we studied the prevalence of infection in this population, and specifically the prevalence of infection by the more virulent, cagA-positive strains (CAP). 140 sub-Saharan immigrants recently arrived to Gran Canaria (Canary Islands, Spain) were studied. 80.7% were male, with a mean age of 24.2 y. 90.7% tested seropositive for HP and 72.2% of them carried antibodies against the 'pathogenicity island' cagA. We did not find any relationship between the presence of these antibodies and the clinical variables studied. We can conclude that HP infection is virtually universal in this population, with a high percentage of infection by CAP strains.

Author Keywords

[No Keywords available]

Index Keywords

Nigeria Antigens, Bacterial Cameroon immigrant Africa south of the Sahara human bacterial virulence CagA protein controlled study Ghana Sierra Leone Guinea-Bissau Gambia Democratic Republic Congo Young Adult Humans male Emigrants and Immigrants Spain Benin female Helicobacter infection enzyme linked immunosorbent assay serodiagnosis Article major clinical study adult Helicobacter Infections Dyspepsia Helicobacter pylori Antibodies, Bacterial seroprevalence immunoglobulin G Seroepidemiologic Studies pathogenicity island Bacterial Proteins Mali Cote d'Ivoire
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-50549098600&doi=10.1080%2f00365540801995378&partnerID=40&md5=4f7f5d3730cc1b2936ead43bdf5dfc5c
DOI: 10.1080/00365540801995378
ISSN: 00365548
Cited by: 12
Original Language: English