Medecine et Maladies Infectieuses
Volume 38, Issue 4, 2008, Pages 228-230

Disseminated histoplasmosis revealed by peripheral blood smear in an African immigrant with AIDS [Histoplasmose disséminée révélée par un frottis sanguin chez un immigré africain atteint du sida] (Article)

Débat Zoguéreh D.* , Bigel M.-L. , Billy C. , Perronne V. , Richardin F. , Granier F.
  • a Service de médecine interne, maladies infectieuses et tropicales, hôpital François-Quesnay, 2, boulevard Sully, 78200 Mantes-la-Jolie, France
  • b Service de biologie médicale, hôpital François-Quesnay, 2, boulevard Sully, 78200 Mantes-la-Jolie, France
  • c Service de médecine interne, maladies infectieuses et tropicales, hôpital François-Quesnay, 2, boulevard Sully, 78200 Mantes-la-Jolie, France
  • d Service de médecine interne, maladies infectieuses et tropicales, hôpital François-Quesnay, 2, boulevard Sully, 78200 Mantes-la-Jolie, France
  • e Service de biologie médicale, hôpital François-Quesnay, 2, boulevard Sully, 78200 Mantes-la-Jolie, France
  • f Service de médecine interne, maladies infectieuses et tropicales, hôpital François-Quesnay, 2, boulevard Sully, 78200 Mantes-la-Jolie, France

Abstract

We report a case of disseminated histoplasmosis due to Histoplasma capsulatum var. capsulatum in an African patient with AIDS (born in Ghana) and living in France. This opportunistic fungal infection has never been reported in Ghana, maybe because of limited means of investigation or ignorance. Nevertheless, it was reported in a Ghanaian immigrant living in Italy. In our patient, the first diagnosis was suggested by a peripheral blood smear, which is not a classical biological diagnostic method. The diagnostic interest and the frequency of positive peripheral blood smears in the course of disseminated histoplasmosis are probably under estimated. © 2007.

Author Keywords

AIDS Opportunistic fungal infection Peripheral blood smear Disseminated histoplasmosis

Index Keywords

immigrant France histoplasma capsulatum histoplasmosis clinical feature human AIDS-Related Opportunistic Infections blood smear Ghana opportunistic infection African American laboratory test Humans blood culture clinical examination male case report Article adult itraconazole acquired immune deficiency syndrome amphotericin B lipid complex
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-43049162190&doi=10.1016%2fj.medmal.2007.10.009&partnerID=40&md5=e946771f4fddbfa2f13d9a1302c7ebe3
DOI: 10.1016/j.medmal.2007.10.009
ISSN: 0399077X
Cited by: 1
Original Language: French