Clinical Infectious Diseases
Volume 46, Issue 3, 2008, Pages 443-446

Vitamin D deficiency is associated with tuberculosis and latent tuberculosis infection in immigrants from sub-Saharan Africa (Article) (Open Access)

Gibney K.B.* , MacGregor L. , Leder K. , Torresi J. , Marshall C. , Ebeling P.R. , Biggs B.-A.
  • a Victorian Infectious Diseases Service, Service Evaluation Unit, Royal Melbourne Hospital, Melbourne, VIC, Australia, Royal Darwin Hospital, PO Box 41326, Casuarina, NT 0810, Australia
  • b Clinical Epidemiology and Health, Service Evaluation Unit, Royal Melbourne Hospital, Melbourne, VIC, Australia
  • c Victorian Infectious Diseases Service, Service Evaluation Unit, Royal Melbourne Hospital, Melbourne, VIC, Australia, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia
  • d Victorian Infectious Diseases Service, Service Evaluation Unit, Royal Melbourne Hospital, Melbourne, VIC, Australia, Department of Medicine, Western Hospital, University of Melbourne, Melbourne, VIC, Australia
  • e Victorian Infectious Diseases Service, Service Evaluation Unit, Royal Melbourne Hospital, Melbourne, VIC, Australia, Centre for Clinical Research Excellence in Infectious Diseases, Western Hospital, University of Melbourne, Melbourne, VIC, Australia
  • f Department of Medicine, Western Hospital, University of Melbourne, Melbourne, VIC, Australia
  • g Victorian Infectious Diseases Service, Service Evaluation Unit, Royal Melbourne Hospital, Melbourne, VIC, Australia, Department of Medicine, Western Hospital, University of Melbourne, Melbourne, VIC, Australia, Centre for Clinical Research Excellence in Infectious Diseases, Western Hospital, University of Melbourne, Melbourne, VIC, Australia

Abstract

Among African immigrants in Melbourne, Victoria, Australia, we demonstrated lower geometric mean vitamin D levels in immigrants with latent tuberculosis infection than in those with no Mycobacterium tuberculosis infection (P = .007); such levels were also lower in immigrants with tuberculosis or past tuberculosis than in those with latent tuberculosis infection (P < .001). Higher vitamin D levels were associated with lower probability of any M. tuberculosis infection (P < .001) and lower probability of tuberculosis or past tuberculosis (compared with latent tuberculosis infection; P = .001). © 2008 by the Infectious Diseases Society of America. All rights reserved.

Author Keywords

[No Keywords available]

Index Keywords

immigrant Africa south of the Sahara Australia human middle aged controlled study priority journal probability Mycobacterium tuberculosis Aged Humans Adolescent male Emigrants and Immigrants female tuberculosis Risk Factors Africa vitamin D deficiency Article Retrospective Studies major clinical study adult infection sensitivity
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-39349099303&doi=10.1086%2f525268&partnerID=40&md5=b1d73fa17da2fc8bc13d9fcc5c8f77d9
DOI: 10.1086/525268
ISSN: 10584838
Cited by: 162
Original Language: English