Endocrinologia y Nutricion
Volume 55, Issue 10, 2008, Pages 454-458

Diabetes mellitus in young immigrants from Hindustan. A descriptive study [Diabetes mellitus en inmigrantes indostanos jóvenes. Un estudio descriptivo] (Article)

Nadal J.F. , Peinado R.M. , Calafell N.R. , Aparicio C.C. , Martos A.M.M. , Griera J.M.
  • a EAP Raval Sud, Barcelona, Spain, EAP Raval Sud, CAP Drassanes (ICS), Avda. Drassanes, 17-21, 08001 Barcelona, Spain
  • b EAP Raval Sud, Barcelona, Spain
  • c EAP Raval Sud, Barcelona, Spain
  • d EAP Raval Sud, Barcelona, Spain
  • e EAP Raval Sud, Barcelona, Spain
  • f EAP Raval Sud, Barcelona, Spain

Abstract

Aim: To analyze the physiological and clinical characteristics of diabetes mellitus (DM) in young immigrants from Hindustan. Material and methods: We performed a descriptive analysis of clinical and laboratory variables related to DM in diabetic Hindustanis aged between 15 and 40 years old. Body mass index (BMI) and waist perimeter (WP) were calculated. The immunology of DM and baseline C-peptide were studied and insulin resistance (IR) was determined by Homeostasis Model Assessment: Insulin Resistance (HOMA-IR). Results: The final sample consisted of 30 patients. The prevalence of DM was 0.84%. All patients had DM2 and 50% had high IR. Baseline C-peptide secretion was preserved in all patients. The cut-off points that best predicted IR in this ethnic group were a BMI higher than 25 and a WC of more than 95 cm. Conclusions: Most young Hindustani immigrants with diabetes have DM2 with preserved baseline insulin secretion and IR. Lower degrees of obesity than in the Spanish population were associated with IR.

Author Keywords

Pathophysiology Insulin resistance Immigrant Ethnicity Diabetes mellitus

Index Keywords

diabetes mellitus controlled study immigrant pathophysiology insulin resistance adult ethnicity insulin release clinical article India body mass prevalence Article Waist Circumference clinical feature human C peptide Adolescent
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-58149330243&doi=10.1016%2fS1575-0922%2808%2975842-X&partnerID=40&md5=2496bbbdb78eca6d162b7669e0c49cc2
DOI: 10.1016/S1575-0922(08)75842-X
ISSN: 15750922
Cited by: 2
Original Language: Spanish