AIDS Patient Care and STDs
Volume 31, Issue 12, 2017, Pages 528-534

Factors Associated with Use of Short-Term Pre-Exposure Prophylaxis for HIV among Female Partners of Migrant Miners in Mozambique (Review)

Falcao J.* , Zerbe A. , Lahuerta M. , Baggaley R. , Ahoua L. , Dimattei P. , Morales F. , Ramiro I. , El-Sadr W.M.
  • a Mailman School of Public Health, ICAP, Columbia University, 722 West 168th Street, New York, NY 10032, United States
  • b Mailman School of Public Health, ICAP, Columbia University, 722 West 168th Street, New York, NY 10032, United States
  • c Mailman School of Public Health, ICAP, Columbia University, 722 West 168th Street, New York, NY 10032, United States, Department of HIV, World Health Organization (WHO), Geneva, Switzerland
  • d Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States
  • e Mailman School of Public Health, ICAP, Columbia University, 722 West 168th Street, New York, NY 10032, United States
  • f Mailman School of Public Health, ICAP, Columbia University, 722 West 168th Street, New York, NY 10032, United States
  • g Mailman School of Public Health, ICAP, Columbia University, 722 West 168th Street, New York, NY 10032, United States
  • h Ministry of Health, Maputo, Mozambique
  • i Mailman School of Public Health, ICAP, Columbia University, 722 West 168th Street, New York, NY 10032, United States, Department of HIV, World Health Organization (WHO), Geneva, Switzerland

Abstract

Effective interventions tailored to specific types of behaviors and contexts are needed for women at risk for HIV acquisition. Oral pre-exposure prophylaxis (PrEP) is an efficacious HIV prevention intervention that uses antiretroviral drugs to reduce the risk of acquiring HIV infection. In Mozambique, HIV remains a major public health concern, with a national prevalence of 13%. Studies have demonstrated that the migration of male miners between southern provinces of Mozambique and South Africa is contributing to the HIV epidemic in Mozambique. This increased risk is associated with the engagement of male miners, while separated from their partners, in sexual relationships with other women, including transactional sex workers, in a hyperendemic setting in South Africa. We conducted 25 in-depth interviews with a subset of female partners in a stable relationship with migrant miners participating in a prospective cohort study to assess the feasibility, acceptability, and adherence to daily oral short-term PrEP. Drug levels were available for the participants, as reported in an earlier study. Interviews were recorded, transcribed, and submitted for qualitative thematic analysis. The major themes identified were the benefits of taking PrEP, the ease of taking daily PrEP, the reluctance to disclose PrEP use to partners, the lack of changes in sexual behavior, and prevailing gender dynamics and how they impact women's ability to access PrEP and other HIV prevention interventions. © Copyright 2017, Mary Ann Liebert, Inc.

Author Keywords

PrEP Women Mozambique HIV qualitative

Index Keywords

prospective study HIV Infections sexual behavior Human immunodeficiency virus infection alanine aminotransferase Safe Sex follow up human clinical assessment sexuality middle aged Sexual Partners Prospective Studies statistics and numerical data Self Report Anti-Retroviral Agents antiretrovirus agent medication compliance Human immunodeficiency virus sex worker qualitative research Human immunodeficiency virus prevalence South Africa interview condom use Humans migrant psychology Interviews as Topic male occupation female Mozambique Review short course therapy pill emtricitabine tenofovir miner infection prevention thematic analysis adult transactional sex migration major clinical study sexual intercourse antiretroviral therapy cohort analysis Transients and Migrants dried blood spot testing pre-exposure prophylaxis
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85038227863&doi=10.1089%2fapc.2017.0179&partnerID=40&md5=ea7921d4619da634956e3b98bcee92c6
DOI: 10.1089/apc.2017.0179
ISSN: 10872914
Cited by: 3
Original Language: English