Clinical Rheumatology
Volume 36, Issue 5, 2017, Pages 1091-1102

Gout in immigrant groups: a cohort study in Sweden (Article) (Open Access)

Wändell P.* , Carlsson A.C. , Li X. , Gasevic D. , Ärnlöv J. , Holzmann M.J. , Sundquist J. , Sundquist K.
  • a Department of Neurobiology, Care Sciences and Society, Division of Family Medicine, Karolinska Institutet, Alfred Nobels Allé 23, Huddinge, SE-141 83, Sweden
  • b Department of Neurobiology, Care Sciences and Society, Division of Family Medicine, Karolinska Institutet, Alfred Nobels Allé 23, Huddinge, SE-141 83, Sweden, Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden
  • c Center for Primary Health Care Research, Lund University, Malmö, Sweden
  • d Usher Institute of Population Health Sciences and Informatics, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, United Kingdom
  • e Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden
  • f Department of Emergency Medicine, Karolinska University Hospital, Huddinge, Sweden, Department of Internal Medicine Solna, Karolinska Institutet, Stockholm, Sweden
  • g Center for Primary Health Care Research, Lund University, Malmö, Sweden
  • h Center for Primary Health Care Research, Lund University, Malmö, Sweden

Abstract

Our aim was to study the association between country of birth and incidence of gout in different immigrant groups in Sweden. The study population included the whole population of Sweden. Gout was defined as having at least one registered diagnosis in the National Patient Register. The association between incidence of gout and country of birth was assessed by Cox regression, with hazard ratios (HRs) and 95% confidence intervals (95% CI), using Swedish-born individuals as referents. All models were conducted in both men and women, and the full model was adjusted for age, place of residence in Sweden, educational level, marital status, neighbourhood socio-economic status and co-morbidities. The risk of gout varied by country of origin, with highest estimates, compared to Swedish born, in fully adjusted models among men from Iraq (HR 1.82, 95% CI 1.54–2.16), and Russia (HR 1.69, 95% CI 1.26–2.27), and also high among men from Austria, Poland, Africa and Asian countries outside the Middle East; and among women from Africa (HR 2.23, 95% CI 1.50–3.31), Hungary (HR 1.98, 95% CI 1.45–2.71), Iraq (HR 1.76, 95% CI 1.13–2.74) and Austria (HR 1.70, 95% CI 1.07–2.70), and also high among women from Poland. The risk of gout was lower among men from Greece, Spain, Nordic countries (except Finland) and Latin America and among women from Southern Europe, compared to their Swedish counterparts. The increased risk of gout among several immigrant groups is likely explained by a high cardio-metabolic risk factor pattern needing attention. © 2017, The Author(s).

Author Keywords

Socio-economic status Second-generation immigrants Gender Neighbourhood Gout First-generation immigrants

Index Keywords

Romania immigrant South and Central America Registries multicenter study clinical trial Population Surveillance register human epidemiology risk assessment middle aged Middle East Cohort Studies Ethnic Groups Poland Turkey (republic) Iraq priority journal ethnic group Aged Yugoslavia Austria ethnology gout procedures Hungary Sweden Humans migrant male Emigrants and Immigrants Spain female Aged, 80 and over very elderly risk factor Risk Factors Africa Greece Incidence Article Southern Europe major clinical study adult cohort analysis Russian Federation health survey
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85010788252&doi=10.1007%2fs10067-016-3525-1&partnerID=40&md5=62ab68fb72d89ca45c553388eb8fb8a2
DOI: 10.1007/s10067-016-3525-1
ISSN: 07703198
Cited by: 1
Original Language: English