International Journal of Infectious Diseases
Volume 56, 2017, Pages 45-53

The global dynamics of diabetes and tuberculosis: the impact of migration and policy implications (Review) (Open Access)

Girardi E. , Sañé Schepisi M. , Goletti D. , Bates M. , Mwaba P. , Yeboah-Manu D. , Ntoumi F. , Palmieri F. , Maeurer M. , Zumla A. , Ippolito G.*
  • a National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, Rome, 00149, Italy
  • b National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, Rome, 00149, Italy
  • c National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, Rome, 00149, Italy
  • d Division of Infection and Immunity, University College London; and National Institute of Health Research Biomedical Research Centre at UCL Hospitals, London, United Kingdom, UNZA-UCLMS Research and Training Program, University Teaching HospitalLusaka, Zambia
  • e UNZA-UCLMS Research and Training Program, University Teaching HospitalLusaka, Zambia
  • f Department of Bacteriology, Noguchi Memorial Institute for Medical Research, Accra, Ghana
  • g Fondation Congolaise pour la Recherche Médicale, Faculté des Sciences de la Santé, Marien Ngouabi University; and Faculté des Sciences et Techniques, Marien Ngouabi University, Brazzaville, Congo, Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany
  • h National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, Rome, 00149, Italy
  • i Therapeutic Immunology (TIM) Division, Department of Laboratory Medicine, Karolinska University Hospital Huddinge; and Centre for Allogeneic Stem Cell Transplantation, Karolinska University Hospital Huddinge, Stockholm, Sweden
  • j Division of Infection and Immunity, University College London; and National Institute of Health Research Biomedical Research Centre at UCL Hospitals, London, United Kingdom, UNZA-UCLMS Research and Training Program, University Teaching HospitalLusaka, Zambia, International Public Health Crisis Group (IPHCG), Italy
  • k National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, Rome, 00149, Italy, International Public Health Crisis Group (IPHCG), Italy

Abstract

The convergence between tuberculosis (TB) and diabetes mellitus (DM) will represent a major public health challenge in the near future. DM increases the risk of developing TB by two to three times and also increases the risk of TB treatment failure, relapse, and death. The global prevalence of DM is predicted to rise significantly in the next two decades, particularly in some of the low- and middle-income countries with the highest TB burden. Migration may add further complexity to the effort to control the impact on TB of the growing DM pandemic. Migration may increase the risk of DM, although the magnitude of this association varies according to country of origin and ethnic group, due to genetic factors and lifestyle differences. Migrants with TB may have an increased prevalence of DM compared to the native population, and the risk of TB among persons with DM may be higher in migrants than in autochthonous populations. Screening for DM among migrants, screening migrants with DM for active and latent TB, and improving access to DM care, could contribute to mitigate the effects of DM on TB. © 2017 The Authors

Author Keywords

Communicable diseases diabetes Migrants tuberculosis

Index Keywords

metformin Forecasting lifestyle Human immunodeficiency virus infection Human Migration health care policy non insulin dependent diabetes mellitus human comorbidity diabetes mellitus multidrug resistant tuberculosis antiretrovirus agent Dynamics screening test epidemiological data disease surveillance diabetic patient Humans migrant tuberculostatic agent Tuberculosis, Pulmonary latent tuberculosis tuberculosis risk factor Review prevalence Incidence epidemic migration health care quality health care access heredity tuberculosis control public policy disease association public health
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85013435787&doi=10.1016%2fj.ijid.2017.01.018&partnerID=40&md5=eb7389e66c26535308bfacc181a63072
DOI: 10.1016/j.ijid.2017.01.018
ISSN: 12019712
Cited by: 20
Original Language: English