Journal of Affective Disorders
Volume 210, 2017, Pages 174-180

Prevalence and clinical severity of mood disorders among first-, second- and third-generation migrants (Article)

Pignon B.* , Alexis Geoffroy P. , Thomas P. , Roelandt J.-L. , Rolland B. , Morgan C. , Vaiva G. , Amad A.
  • a Univ. Lille, CNRS, CHU LILLE, UMR9193-PsychiC-SCALab, UMR9193-PsychiC-SCALab, Psychiatry Department, Lille, F-59000, France
  • b Inserm, U1144, Paris, F-75006, France, Paris Descartes University, UMR-S 1144, Paris, F-75006, France, Paris Diderot University, Sorbonne Paris Cité, UMR-S 1144, Paris, F-75013, France, AP-HP, GH Saint-Louis – Lariboisière – F. Widal, Psychiatry and Addiction Medicine Department, Paris Cedex 10, 75475, France
  • c Univ. Lille, CNRS, CHU LILLE, UMR9193-PsychiC-SCALab, UMR9193-PsychiC-SCALab, Psychiatry Department, Lille, F-59000, France, Federation of Mental Health Research, Lille, France, INSERM 1123, Equipe ECEVE, Paris, France
  • d World Health Organization Collaborative Centre (WHO-CC), EPSM Lille-Metropole, Lille, France, INSERM 1123, Equipe ECEVE, Paris, France
  • e Univ. Lille, CNRS, CHU LILLE, UMR9193-PsychiC-SCALab, UMR9193-PsychiC-SCALab, Psychiatry Department, Lille, F-59000, France, Univ. Lille, INSERM, CHU LILLE, U1171, Department of Addiction Medicine - Addiction Consultation Liaison Unit, Pôle de Psychiatrie, Lille, F-59000, France
  • f King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, United Kingdom
  • g Univ. Lille, CNRS, CHU LILLE, UMR9193-PsychiC-SCALab, UMR9193-PsychiC-SCALab, Psychiatry Department, Lille, F-59000, France, Federation of Mental Health Research, Lille, France
  • h Univ. Lille, CNRS, CHU LILLE, UMR9193-PsychiC-SCALab, UMR9193-PsychiC-SCALab, Psychiatry Department, Lille, F-59000, France, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, United Kingdom

Abstract

Background The role of migration as a risk factor remains unknown for mood disorders because of poor data. We sought to examine the prevalence and severity of mood disorders (bipolar disorder (BD), unipolar depressive disorder (UDD) and dysthymia) in first, second, and third generation migrants in France. Methods The Mental Health in the General Population survey interviewed 38,694 individuals. The prevalence of lifetime mood disorders, comorbidities, and clinical features was compared between migrants and non-migrants and by generation. All analyses were adjusted for age, sex and level of education. Results The prevalence of any lifetime mood disorder was higher in migrants compared with non-migrants (OR=1.36, 95% CI [1.27–1.45]). This increased prevalence was significant for UDD (OR=1.44, 95% CI [1.34–1.54]), but not for BD (OR=1.15, 95% CI [0.96–1.36]) or dysthymia (OR=1.09, 95% CI [0.94–1.27]), although the prevalence of BD was increased in the third generation (OR=1.27, 95% CI [1.01–1.60]). Migrants with BD or UDD were more likely to display a comorbid psychotic disorder compared to non-migrants with BD or UDD. Cannabis-use disorders were more common in migrant groups for the 3 mood disorders, whereas alcohol-use disorders were higher in migrants with UDD. Posttraumatic stress disorder was more frequent among migrants with UDD. Limitations The study used cross-sectional prevalence data and could be biased by differences in the course of disease according to migrant status. Moreover, this design does not allow causality conclusion or generalization of the main findings. Conclusion Mood disorders are more common among migrants, especially UDD. Moreover, migrants with mood disorders presented with a more severe profile, with increased rates of psychotic and substance-use disorders. © 2016

Author Keywords

Depressive disorder Migration Dysthymia bipolar disorder Comorbidities

Index Keywords

mood disorder France clinical feature human epidemiology comorbidity middle aged controlled study priority journal Substance-Related Disorders alcoholism unipolar depressive disorder drug dependence dysthymia ethnology bipolar disorder Cross-Sectional Studies cross-sectional study migrant Humans male Emigrants and Immigrants female risk factor Risk Factors prevalence Article major clinical study adult migration posttraumatic stress disorder disease severity Transients and Migrants Depressive Disorder, Major major depression Mood Disorders
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85007477346&doi=10.1016%2fj.jad.2016.12.039&partnerID=40&md5=f0892d1a027e89644227e7b7f3642c1e
DOI: 10.1016/j.jad.2016.12.039
ISSN: 01650327
Cited by: 13
Original Language: English