Gynecological Endocrinology
Volume 30, Issue 1, 2014, Pages 74-77

Observational study of vitamin D levels and pain in pregnant immigrant women living in Sweden (Article)

Bergström I.* , Palmér M. , Persson J. , Blanck A.
  • a Centre for Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Huddinge, S-141 86 Stockholm, Sweden, Department of Clinical Science, Intervention and Technology, Karolinska University Hospital, Huddinge, Stockholm, Sweden
  • b Centre for Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Huddinge, S-141 86 Stockholm, Sweden
  • c Department of Anaesthesia and Intensive Care, Karolinska University Hospital, Huddinge, Stockholm, Sweden
  • d Department of Clinical Science, Intervention and Technology, Karolinska University Hospital, Huddinge, Stockholm, Sweden

Abstract

The aim was to determine the prevalence of vitamin D insufficiency in pregnant immigrant women assessed by the levels of 25-hydroxyvitamin D, parathyroid hormone (PTH) and alkaline phosphatase (ALP) as well as the correlation to musculoskeletal pain. Sixty-eight pregnant immigrant women were included. Fifty-one native Swedish pregnant women served as controls. 25-hydroxyvitamin D, PTH, ALP and musculoskeletal pain, rated on a visual analogue scale, were analyzed in all women in gestational week 12 and in the immigrant women at 6-12 months postpartum. A significantly higher proportion of immigrant women (77.9%) had levels of 25-hydroxyvitamin D <25 nmol/l compared with 3.9% in controls. Of the immigrant women, 29.4% had 25-hydroxyvitamin D levels <12 nmol/l, but none of the controls. Musculoskeletal pain evaluated with a visual analogue scale (VAS) was significantly higher for the immigrant women than for the controls at gestational week 12. However, no within group correlation was seen between 25-hydroxyvitamin D levels, PTH or ALP and pain. A significant negative correlation between changes in 25-hydroxyvitamin D and pain from gestational week 12 to postpartum was observed. Hypovitaminosis D is prevalent in immigrant women living in Sweden. There is an indication that pain might be associated with hypovitaminosis D. © 2014 Informa UK Ltd.

Author Keywords

Postpartum period immigrants Pregnancy Musculoskeletal pain Vitamin D deficiency

Index Keywords

immigrant Pregnancy Complications vitamin blood level human Pregnant Women Vitamin D controlled study pain priority journal alkaline phosphatase Sweden Young Adult parathyroid hormone Humans Adolescent 25 hydroxyvitamin D Emigrants and Immigrants female musculoskeletal pain observational study pregnancy vitamin D deficiency Article major clinical study adult pregnant woman Case-Control Studies visual analog scale postpartum pain nutritional status pain assessment gestational age
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84890480103&doi=10.3109%2f09513590.2013.856408&partnerID=40&md5=79a5b0a6c137e5d3e799e32fa0d9967a
DOI: 10.3109/09513590.2013.856408
ISSN: 09513590
Cited by: 8
Original Language: English